Chen H, Ni Z, Jing D, He L, Qiao L, Liu L, Wei X, Jiang M, Tang S, Xu H
Department of Digestion, General Hospital of Chengdu Military Command, Chengdu, Sichuan Province, China.
Department of Biomedical Engineering, Fourth Military Medical University, Xi'an, China.
Dis Esophagus. 2017 Feb 1;30(3):1-5. doi: 10.1111/dote.12446.
The placement of metal stents is often used as a palliative treatment for malignant esophageal stenosis. We designed a novel stent that has been used clinically since 2011, and we therefore performed a retrospective study to compare the therapeutic effects of this novel metal stent to a conventional partially covered metal stent in patients with malignant esophageal strictures. The records of 201 consecutive patients who underwent placement of either the conventional partially covered metal stents (Group A, n = 92) or the new metal stents (Group B, n = 109) in the Endoscopy Center of General Hospital of Chengdu Military Command from October 2008 to March 2013 were reviewed. The median dysphagia score significantly improved in both groups 1 week following stent placement (P < 0.001). No significant differences were observed in success rate (P = 0.910) or the complication rate (P = 0.426) between groups. Six months after stent placement, recurrent dysphagia due to stent migration, tissue ingrowth or overgrowth or food obstruction occurred in 45% and 29% of patients in the conventional stent and new stent groups, respectively. The results of this retrospective study indicate that the new modified self-expandable metal stents (SEMS) is at least as safe and effective as the conventional partially covered SEMS in treatment of malignant esophageal strictures.
金属支架置入术常用于恶性食管狭窄的姑息治疗。我们设计了一种自2011年起开始临床应用的新型支架，因此进行了一项回顾性研究，比较这种新型金属支架与传统部分覆膜金属支架对恶性食管狭窄患者的治疗效果。回顾了2008年10月至2叭3年3月在成都军区总医院内镜中心接受传统部分覆膜金属支架置入术（A组，n = 92）或新型金属支架置入术（B组，n = 109）的201例患者的记录。两组患者在支架置入术后1周吞咽困难评分中位数均显著改善（P < 0.001）。两组间成功率（P = 0.910）及并发症发生率（P = 0.426）差异均无统计学意义。支架置入术后6个月，传统支架组和新型支架组分别有45%和29%的患者因支架移位、组织向内生长或过度生长或食物阻塞而再次出现吞咽困难。这项回顾性研究结果表明，新型改良自膨式金属支架（SEMS）在治疗恶性食管狭窄方面至少与传统部分覆膜SEMS一样安全有效。
