Barsegian O K, Sotnikova N Iu
Akush Ginekol (Mosk). 1989 Jun(6):23-7.
A total of 70 females with threatened abortions induced by hormonal, infectious or unclear factors and 63 second trimester underwent clinical, hormonal and immunological investigations. In all females with threatened abortion, the study revealed the variance in immunological data in accordance with the term of pregnancy and cause of its incompetence. The lesser degree of immunological impairment was documented in the females whose pregnancy was complicated by hormonal disorders, whereas females with a history of infections in the early pregnancy demonstrated more profound immunological shifts. In those patients whose pregnancy was lost in the first trimester and the cause of the wastage remained unclear, the authors noted elevated T and decreased B lymphocytes, as well as dramatically reduced leukocyte migration inhibition factor.
共有70名因激素、感染或不明因素导致先兆流产的女性以及63名孕中期女性接受了临床、激素和免疫学检查。在所有先兆流产女性中，研究发现免疫数据根据孕周及其功能不全的原因存在差异。妊娠合并激素紊乱的女性免疫损伤程度较轻，而孕早期有感染史的女性免疫变化更为显著。在那些孕早期流产且流产原因不明的患者中，作者注意到T淋巴细胞升高、B淋巴细胞减少，以及白细胞迁移抑制因子显著降低。
