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特比萘芬诱发的玫瑰糠疹样皮疹。

Terbinafine induced pityriasis rosea-like eruption.

作者信息

George Anisha, Bhatia Anuradha, Kanish Bimal, Williams Abhilasha

机构信息

Department of Dermatology, Christian Medical College, Ludhiana, Punjab, India.

出版信息

Indian J Pharmacol. 2015 Nov-Dec;47(6):680-1. doi: 10.4103/0253-7613.169574.

DOI:10.4103/0253-7613.169574
PMID:26729964
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC4689026/
Abstract

Terbinafine is an allylamine antifungal agent which is widely used for the treatment of fungal infections. Cutaneous side effects have been reported in 2% of the patients on terbinafine therapy with many morphological patterns. We report a case of terbinafine induced pityriasis rosea, a very rare side effect of terbinafine. This report emphasizes the importance of counseling the patient to report immediately in the event of a cutaneous eruption.

摘要

特比萘芬是一种烯丙胺类抗真菌药物，广泛用于治疗真菌感染。据报道，接受特比萘芬治疗的患者中有2%出现皮肤副作用，且有多种形态学表现。我们报告一例特比萘芬诱发的玫瑰糠疹，这是特比萘芬一种非常罕见的副作用。本报告强调了告知患者在出现皮肤皮疹时应立即报告的重要性。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/4bfb/4689026/f9fa21c43505/IJPharm-47-680-g001.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/4bfb/4689026/f9fa21c43505/IJPharm-47-680-g001.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/4bfb/4689026/f9fa21c43505/IJPharm-47-680-g001.jpg

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本文引用的文献

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Int J Dermatol. 2013 Sep;52(9):1155-6. doi: 10.1111/j.1365-4632.2011.05117.x. Epub 2012 Sep 24.
2
Pityriasis rosea: an important papulosquamous disorder.玫瑰糠疹：一种重要的丘疹鳞屑性疾病。
Int J Dermatol. 2005 Sep;44(9):757-64. doi: 10.1111/j.1365-4632.2005.02635.x.
3
Subacute lupus erythematosus-like eruption due to terbinafine: report of three cases.特比萘芬所致亚急性红斑狼疮样皮疹：3例报告
Indian Dermatol Online J. 2019 Mar-Apr;10(2):125-130. doi: 10.4103/idoj.IDOJ_353_18.
4
CYP2C19 and 3A4 Dominate Metabolic Clearance and Bioactivation of Terbinafine Based on Computational and Experimental Approaches.基于计算和实验方法，CYP2C19 和 3A4 主导特比萘芬的代谢清除和生物活化。
Chem Res Toxicol. 2019 Jun 17;32(6):1151-1164. doi: 10.1021/acs.chemrestox.9b00006. Epub 2019 Apr 10.
5
Reply: Commentary on letter to the editor from Drago et al.回复：对德拉戈等人致编辑信件的评论
JAAD Case Rep. 2018 Sep 18;4(8):817. doi: 10.1016/j.jdcr.2018.04.001. eCollection 2018 Sep.
6
Allergic Maculo-Papular Exanthema Due To Terbinafine.特比萘芬引起的变应性斑丘疹性皮疹
Open Access Maced J Med Sci. 2017 Jul 20;5(4):535-536. doi: 10.3889/oamjms.2017.105. eCollection 2017 Jul 25.
Br J Dermatol. 2003 May;148(5):1056. doi: 10.1046/j.1365-2133.2003.05235.x.
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Adverse drug reactions of the new oral antifungal agents--terbinafine, fluconazole, and itraconazole.新型口服抗真菌药物——特比萘芬、氟康唑和伊曲康唑的药物不良反应。
Int J Dermatol. 1998 Jun;37(6):410-5. doi: 10.1046/j.1365-4362.1998.00496.x.
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Cutaneous adverse effects associated with terbinafine therapy: 10 case reports and a review of the literature.与特比萘芬治疗相关的皮肤不良反应：10例病例报告及文献综述
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