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药师对抗癫痫药物治疗知识的评估。

An evaluation of pharmacist knowledge on treatment with antiepileptic drugs.

作者信息

Roth Yifat, Neufeld Miri Y, Blatt Ilan, Guy-Alfandary Shiri, Rasaby Sivan, Ekstein Dana, Eyal Sara

机构信息

Division of Clinical Pharmacy, School of Pharmacy, The Hebrew University of Jerusalem, Jerusalem, Israel.

EEG and Epilepsy Unit, Department of Neurology, Tel-Aviv Sourasky Medical Center, Sackler Faculty of Medicine, Tel Aviv University, Tel Aviv, Israel.

出版信息

Seizure. 2016 Jan;34:60-5. doi: 10.1016/j.seizure.2015.11.007. Epub 2015 Nov 29.

Abstract

PURPOSE

As pharmacists play an important role in managing antiepileptic drug (AED) therapy, they should be aware of different aspects of the treatment. Our aim was to evaluate pharmacists' knowledge of the pharmacological treatment of epilepsy, and their recommendations under hypothetical situations, through a written questionnaire.

METHODS

The questionnaire included 22 questions divided into three sections: demographic data (eight questions), knowledge of specific aspects of AED therapy (true/false; four questions), and actions taken in theoretical situations involving AED therapy (multiple choice; ten questions). The questionnaire was distributed to pharmacists practicing in Israel and working in pharmacies and/or participating in professional meetings and continued education programs.

RESULTS

One hundred and twenty one pharmacists completed the questionnaire (response rate 19%). The mean overall score was 48 ± 15% correct answers. Most pharmacists were aware of the need to continue AED treatment during pregnancy, the risk of generic switches, and the need to call the physician for loss of seizure control (92%, 89% and 81% of responders, respectively). Twelve percent identified correctly all three situations in which the clinicians should be contacted urgently, and 27% did not identify any of them. The total score was related to the academic degree (PharmD vs. other) and to the duration since training completion.

CONCLUSION

Pharmacists were knowledgeable regarding some aspects of care of people with epilepsy. However, our study, as in previous studies among health care professionals, identified some gaps in knowledge. These findings indicate the need for better education of pharmacists regarding epilepsy and its treatment.

摘要

目的

由于药剂师在抗癫痫药物(AED)治疗管理中发挥着重要作用,他们应了解治疗的不同方面。我们的目的是通过一份书面问卷评估药剂师对癫痫药物治疗的知识,以及他们在假设情况下的建议。

方法

问卷包括22个问题,分为三个部分:人口统计学数据(8个问题)、AED治疗特定方面的知识(是非题;4个问题)以及在涉及AED治疗的理论情况下采取的行动(选择题;10个问题)。问卷分发给在以色列执业、在药店工作和/或参加专业会议及继续教育项目的药剂师。

结果

121名药剂师完成了问卷(回复率19%)。平均总分是正确答案的48±15%。大多数药剂师意识到孕期继续进行AED治疗的必要性、通用名药物转换的风险以及癫痫发作控制丧失时联系医生的必要性(分别为92%、89%和81%的回复者)。12%的人正确识别了所有三种应紧急联系临床医生的情况,27%的人一种情况都未识别。总分与学术学位(药学博士与其他)以及完成培训后的时长有关。

结论

药剂师在癫痫患者护理的某些方面知识丰富。然而,我们的研究,如同之前在医疗保健专业人员中的研究一样,发现了一些知识空白。这些发现表明需要对药剂师进行更好的癫痫及其治疗方面的教育。

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