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苏丹药剂师对抗癫痫药物的了解:一项横断面分析研究。

Knowledge of pharmacists about anti-epileptic drugs in Sudan: a cross-sectional analytical study.

作者信息

Abdelsalam Fatima O, Mohamed Shahd A, Altrafi Asgad A, Balla Doha E, Abdalrahman Abdalrahman M, Atta Awab K, Abdelrahim Abdalfattah M, SeedAhmed Salsabil A, Wedaa Alhumaira, Hamadalneel Yousif B

机构信息

Pharmacy Program, Wad Medani University of Science and Technology, Wad Medani, Sudan.

Department of Clinical Pharmacy and Pharmacy Practice, Faculty of Pharmacy, University of Gezira, Wad Medani, Sudan.

出版信息

J Pharm Health Care Sci. 2025 May 20;11(1):43. doi: 10.1186/s40780-025-00450-5.

Abstract

INTRODUCTION

Pharmacists play essential roles in the use of antiepileptic drugs (AEDs), inadequate knowledge among community and hospital pharmacists regarding AEDs poses a significant challenge in ensuring optimal medication management and patient care.

OBJECTIVE

This study aimed to assess the knowledge of pharmacists about antiepileptic drugs in Sudan.

METHOD

This was a cross-sectional analytical study conducted in Atbara, Gadarif, Kassala, and Port Sudan, Sudan. Using stratified, convenience sampling technique. We collected data directly via a modified, validated English questionnaire from the 1st to the 30th of October 2024.

RESULTS

In total, 384 pharmacists were included. Among them, 300 (78.1%) were under 35 years of age, and the majority of participants were male 213 (55.5%), 157 (40.9%) had a basic bachelor's degree, and 330 (85.9%) received specialized AEDs training. The overall median score of knowledge percentages among participants was 10, with an interquartile range of 30 {25- (-5)}. Only 25 participants (6.5%) demonstrated good knowledge, while a majority of 359 (93.5%) exhibited poor knowledge. There was a statistically significant correlation between years of experience (adjusted odds ratio (AOR) 0.437; 95% CI 0.224-0.855; p value 0.016) and training on AEDs (AOR 0.085; 95% CI 0.031-0.233; p value 0.001) with their level of good knowledge.

CONCLUSION

Our study revealed that the majority of pharmacists in Sudan had a poor level of knowledge about AEDs. The level of knowledge was associated with years of experience and training on AEDs. These results highlight the need for pharmacists to have more training and more exposure to epilepsy and its management.

摘要

引言

药剂师在抗癫痫药物(AEDs)的使用中发挥着重要作用,然而社区和医院药剂师对抗癫痫药物的知识不足,这在确保最佳药物管理和患者护理方面构成了重大挑战。

目的

本研究旨在评估苏丹药剂师对抗癫痫药物的知识水平。

方法

这是一项在苏丹阿特巴拉、加达里夫、卡萨拉和苏丹港进行的横断面分析研究。采用分层便利抽样技术。我们于2024年10月1日至30日通过一份经过修改和验证的英文问卷直接收集数据。

结果

总共纳入了384名药剂师。其中,300名(78.1%)年龄在35岁以下,大多数参与者为男性,共213名(55.5%),157名(40.9%)拥有基础本科学位,330名(85.9%)接受过抗癫痫药物专业培训。参与者知识百分比的总体中位数得分是10,四分位间距为30{25 - (-5)}。只有25名参与者(6.5%)表现出良好的知识水平,而大多数359名(93.5%)表现出较差的知识水平。经验年限(调整优势比(AOR)0.437;95%置信区间0.224 - (此处原文有误,应是0.855);p值0.016)和抗癫痫药物培训(AOR 0.085;95%置信区间0.031 - 0.233;p值0.001)与他们的良好知识水平之间存在统计学上的显著相关性。

结论

我们的研究表明,苏丹大多数药剂师对抗癫痫药物的知识水平较差。知识水平与经验年限和抗癫痫药物培训有关。这些结果凸显了药剂师需要接受更多关于癫痫及其管理的培训和接触。

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