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超声引导下经皮微波消融子宫肌瘤后意外妊娠:一项随访研究。

Unplanned pregnancy after ultrasound-guided percutaneous microwave ablation of uterine fibroids: A follow-up study.

作者信息

Bing-song Zhang, Jing Zhang, Zhi-Yu Han, Chang-tao Xu, Rui-fang Xu, Xiu-mei Li, Hui Liu

机构信息

Department of Interventional Ultrasound, Chinese PLA General Hospital, 28 Fuxing Road, Beijing 100853 China.

出版信息

Sci Rep. 2016 Jan 6;6:18924. doi: 10.1038/srep18924.

Abstract

A follow-up study was performed with 169 women of childbearing age who underwent ultrasound-guided percutaneous microwave ablation (UPMWA) therapy for symptomatic uterine fibroids in the Chinese PLA General Hospital from June 2007 to December 2014. This study aimed to observe the incidence of unplanned pregnancies in these women after UPMWA treatment in order to evaluate its effect on natural conception. Ten unplanned pregnancies in nine women were occurred. Of the nine patients, six did not want the pregnancy and chose for induced abortion to end the pregnancy at an early stage. Three chose to continue with the pregnancy and gave birth to a healthy term infant delivered by cesarean section (of these three patients, two had been previously diagnosed as infertility). None of the patients had any serious obstetric complications. After UPMWA treatment for uterine fibroids, patients may conceive naturally, the impact of the procedure on fertility and pregnancy outcomes is worthy of further prospective study in larger sample.

摘要

2007年6月至2014年12月,在中国人民解放军总医院对169名育龄期妇女进行了一项随访研究,这些妇女因有症状的子宫肌瘤接受了超声引导下经皮微波消融(UPMWA)治疗。本研究旨在观察这些妇女在UPMWA治疗后意外妊娠的发生率,以评估其对自然受孕的影响。9名妇女发生了10次意外妊娠。在这9名患者中,6名不想继续妊娠,选择早期人工流产终止妊娠。3名患者选择继续妊娠,并通过剖宫产分娩出健康的足月婴儿(这3名患者中有2名此前被诊断为不孕症)。所有患者均未出现任何严重的产科并发症。子宫肌瘤经UPMWA治疗后,患者可能自然受孕,该手术对生育能力和妊娠结局的影响值得在更大样本中进行进一步的前瞻性研究。

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