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因症状性子宫肌瘤行子宫动脉栓塞术后妊娠:26例完整妊娠病例系列

Pregnancy following uterine artery embolisation for symptomatic fibroids: a series of 26 completed pregnancies.

作者信息

Carpenter T T, Walker W J

机构信息

Department of Obstetrics and Gynaecology, Royal Surrey County Hospital, Guilford GU2 5XX, UK.

出版信息

BJOG. 2005 Mar;112(3):321-5. doi: 10.1111/j.1471-0528.2004.00414.x.

DOI:10.1111/j.1471-0528.2004.00414.x
PMID:15713147
Abstract

OBJECTIVES

To evaluate the outcome of pregnancies after uterine artery embolisation for uterine fibroids.

DESIGN

Retrospective analysis of pregnancy subsequent to uterine artery embolisation by one interventional radiologist.

SETTING

A UK District General Hospital.

POPULATION

Twenty-nine pregnancies in 671 women who had undergone uterine artery embolisation.

METHODS

Cases were identified by screening questionnaire and from the study database. Detailed information was collected by questionnaires, direct conversations with women and, when necessary, from hospital records.

MAIN OUTCOME MEASURES

Pregnancy outcome, complications and neonatal outcomes.

RESULTS

Of 26 completed pregnancies, detailed information was available for 24 and limited information for 2. Seven (27%) ended in miscarriage, there were two terminations and one ectopic pregnancy. Of 16 deliveries after 24 weeks, first and second trimester bleeding occurred in 40% and 33%, respectively, 4 (25%) had preterm deliveries and the caesarean section rate was 88%. Two (13%) women developed proteinuric hypertension and two others had preterm spontaneous rupture of the membranes. Fourteen of 16 cases were delivered by caesarean section. The rate of primary postpartum haemorrhage was 3/15 (20%). The mean birthweight of term babies was 3.39 kg (SD 0.64) and none required admission to neonatal intensive care. There was one (6.7%) case of fetal growth restriction.

CONCLUSION

Although this study is relatively small, there is an increase in delivery by caesarean section. There does not appear to be any other major excess obstetric associated risk when the demographics of the population in question is considered.

摘要

目的

评估子宫肌瘤子宫动脉栓塞术后的妊娠结局。

设计

由一名介入放射科医生对子宫动脉栓塞术后的妊娠情况进行回顾性分析。

地点

英国一家地区综合医院。

研究对象

671名接受子宫动脉栓塞术的女性中有29例妊娠。

方法

通过筛查问卷和研究数据库确定病例。通过问卷、与女性直接交谈,并在必要时从医院记录中收集详细信息。

主要观察指标

妊娠结局、并发症及新生儿结局。

结果

在26例已完成的妊娠中,24例有详细信息,2例信息有限。7例(27%)以流产告终,2例终止妊娠,1例为宫外孕。在24周后的16例分娩中,孕早期和孕中期出血分别发生在40%和33%的病例中,4例(25%)早产,剖宫产率为88%。2例(13%)女性出现蛋白尿性高血压,另外2例胎膜早破。16例中有14例通过剖宫产分娩。原发性产后出血率为3/15(20%)。足月儿的平均出生体重为3.39 kg(标准差0.64),无一例需要入住新生儿重症监护病房。有1例(6.7%)胎儿生长受限。

结论

尽管本研究规模相对较小,但剖宫产分娩率有所增加。考虑到相关人群的人口统计学特征,似乎没有其他任何与产科相关的重大额外风险。

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