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Improving the correct prescription and dosage of gentamicin.提高庆大霉素的正确处方及剂量。
BMJ Qual Improv Rep. 2012 Aug 3;1(1). doi: 10.1136/bmjquality.u134.w317. eCollection 2012.
2
Using a simple handover to improve the timing of gentamicin levels.采用简单的交接班方式来改善庆大霉素血药浓度监测的及时性。
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A simplified gentamicin dosing chart is quicker and more accurate for nurse verification than the BNFc.对于护士核对而言,一份简化的庆大霉素给药图表比《英国国家处方集儿童版》更快且更准确。
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Effectiveness of an integrated CPOE decision-supporting system with clinical pharmacist monitoring practice in preventing antibiotic dosing errors.具有临床药师监测实践的集成式计算机化医嘱录入决策支持系统在预防抗生素给药错误方面的有效性。
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Validation of a dosage individualization table for extended-interval gentamicin in neonates.验证新生儿延长间隔时间使用庆大霉素的剂量个体化表。
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IMPLEMENTATION OF AN ELECTRONIC PRESCRIPTION CHART FOR GENTAMICIN FOR NEONATAL UNITS AND POSTNATAL WARDS.为新生儿病房和产后病房实施庆大霉素电子处方图表。
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Daily gentamicin using ideal body weight demonstrates lower risk of postpartum endometritis and increased chance of successful outcome compared with traditional 8-hour dosing for the treatment of intrapartum chorioamnionitis.与传统的每8小时给药一次治疗产时绒毛膜羊膜炎相比,使用理想体重计算每日庆大霉素剂量可降低产后子宫内膜炎的风险,并增加成功治疗的几率。
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Does the availability of therapeutic drug monitoring, computerised dose recommendation and prescribing decision support services promote compliance with national gentamicin prescribing guidelines?治疗药物监测、计算机化剂量推荐和处方决策支持服务的可用性是否能促进对国家庆大霉素处方指南的遵守?
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引用本文的文献

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Variation in Gentamicin Dosing and Monitoring in Pediatric Units across New South Wales.新南威尔士州各儿科病房庆大霉素给药与监测的差异
Pediatr Qual Saf. 2017 Feb 17;2(2):e015. doi: 10.1097/pq9.0000000000000015. eCollection 2017 Mar-Apr.
2
Improving Bisphosphonate Infusion Monitoring at Haematology Medical Day Unit.改善血液科日间病房双膦酸盐输注监测
BMJ Qual Improv Rep. 2017 Mar 31;6(1). doi: 10.1136/bmjquality.u206586.w4692. eCollection 2017.
3
Using a simple handover to improve the timing of gentamicin levels.采用简单的交接班方式来改善庆大霉素血药浓度监测的及时性。
BMJ Qual Improv Rep. 2015 Jul 14;4(1). doi: 10.1136/bmjquality.u207727.w3081. eCollection 2015.
4
High prevalence of multiple-antibiotic-resistant (MAR) Escherichia coli in river bed sediments of the Apies River, South Africa.南非阿皮斯河河床沉积物中多重耐药性大肠杆菌的高流行率。
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5
A pre-postintervention study to evaluate the impact of dose calculators on the accuracy of gentamicin and vancomycin initial doses.一项干预前后研究,旨在评估剂量计算器对庆大霉素和万古霉素初始剂量准确性的影响。
BMJ Open. 2015 Jun 4;5(6):e006610. doi: 10.1136/bmjopen-2014-006610.

提高庆大霉素的正确处方及剂量。

Improving the correct prescription and dosage of gentamicin.

作者信息

Qureshi Dr Imran, Habayeb Mr Hani, Grundy Dr Clive

出版信息

BMJ Qual Improv Rep. 2012 Aug 3;1(1). doi: 10.1136/bmjquality.u134.w317. eCollection 2012.

DOI:10.1136/bmjquality.u134.w317
PMID:26734148
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC4652673/
Abstract

Gentamicin is an amino glycoside antibiotic, which is used predominantly in gram-negative infections but also has anti-staphylococcal activity. It is commonly used because of its lack of diffogenicity. There are recognised issues with its dosing of which time is a major factor. A baseline study demonstrated that dosing was only being carried out correctly 30% of the time. This has serious consequences for the treatment of infections. This quality improvement project intervened with the use of a gentamicin calculator, which enabled users to perform three complex mathematical equations simultaneously without error. Post measurement demonstrated that correct dosing had increased to 92%, which was a significant increase.

摘要

庆大霉素是一种氨基糖苷类抗生素,主要用于革兰氏阴性菌感染,但也具有抗葡萄球菌活性。因其缺乏致差异性而被广泛使用。其给药存在一些公认的问题,其中时间是一个主要因素。一项基线研究表明,给药仅30%的时间是正确的。这对感染治疗有严重后果。这个质量改进项目通过使用庆大霉素计算器进行干预,该计算器能让使用者同时无误地进行三个复杂数学方程式的运算。测量后显示正确给药率已升至92%,这是一个显著的提高。