Morton N S
Royal Hospital for Sick Children, Glasgow.
Br J Hosp Med. 1989 Jul;42(1):52-8.
The endogenous surfactant system in the lungs is complex. The synthetic, recycling and metabolic pathways are clear but the controlling mechanisms are not fully understood. Surfactant-specific proteins are important and their isolation and manufacture opens up new prospects for production of a synthetic surfactant with all the properties of natural human surfactant for therapy and prophylaxis of neonatal respiratory distress syndrome.
肺内的内源性表面活性剂系统很复杂。其合成、再循环和代谢途径已明确,但控制机制尚未完全了解。表面活性剂特异性蛋白很重要,其分离和制造为生产具有天然人表面活性剂所有特性的合成表面活性剂用于治疗和预防新生儿呼吸窘迫综合征开辟了新前景。