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对甲基异噻唑啉酮的接触性皮炎

Contact dermatitis to methylisothiazolinone.

作者信息

Scherrer Maria Antonieta Rios, Rocha Vanessa Barreto, Andrade Ana Regina Coelho

机构信息

Universidade Federal de Minas Gerais, Belo Horizonte, MG, Brazil.

出版信息

An Bras Dermatol. 2015 Nov-Dec;90(6):912-4. doi: 10.1590/abd1806-4841.20153992.

DOI:10.1590/abd1806-4841.20153992
PMID:26734880
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC4689087/
Abstract

Methylisothiazolinone (MI) is a preservative found in cosmetic and industrial products. Contact dermatitis caused by either methylchloroisothiazolinone/methylisothiazolinone (MCI/MI or Kathon CG) or MI has shown increasing frequency. The latter is preferably detected through epicutaneous testing with aqueous MI 2000 ppm, which is not included in the Brazilian standard tray. We describe a series of 23 patients tested using it and our standard tray. A case with negative reaction to MCI/MI and positive to MI is emphasized.

摘要

甲基异噻唑啉酮(MI)是一种存在于化妆品和工业产品中的防腐剂。由甲基氯异噻唑啉酮/甲基异噻唑啉酮(MCI/MI或卡松CG)或MI引起的接触性皮炎的发生率呈上升趋势。后者最好通过用2000 ppm的水性MI进行皮肤试验来检测,而这并不包括在巴西标准测试盘中。我们描述了一系列使用该测试方法和我们的标准测试盘进行检测的23例患者。重点介绍了1例对MCI/MI反应阴性但对MI反应阳性的病例。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/7a61/4689087/9f76a1217038/abd-90-06-0912-g02.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/7a61/4689087/855ad1985c4a/abd-90-06-0912-g01.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/7a61/4689087/9f76a1217038/abd-90-06-0912-g02.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/7a61/4689087/855ad1985c4a/abd-90-06-0912-g01.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/7a61/4689087/9f76a1217038/abd-90-06-0912-g02.jpg

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Contact dermatitis to methylisothiazolinone.对甲基异噻唑啉酮的接触性皮炎
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本文引用的文献

1
Increasing trend of sensitization to Methylchloroisothiazolinone/methylisothiazolinone (MCI/MI).对甲基氯异噻唑啉酮/甲基异噻唑啉酮(MCI/MI)致敏的上升趋势。
An Bras Dermatol. 2014 May-Jun;89(3):527-8. doi: 10.1590/abd1806-4841.20142852.
2
Methylchloroisothiazolinone/methylisothiazolinone and methylisothiazolinone allergies can be detected by 200 ppm of methylchloroisothiazolinone/methylisothiazolinone patch test concentration.甲基氯异噻唑啉酮/甲基异噻唑啉酮和甲基异噻唑啉酮过敏可以通过 200ppm 的甲基氯异噻唑啉酮/甲基异噻唑啉酮斑贴试验浓度来检测。
Dermatitis. 2014 May-Jun;25(3):130-4. doi: 10.1097/DER.0000000000000041.
3
从暴露于不同杀菌剂处理的受污染建筑材料中分离出的代谢变化。
Metabolites. 2024 Jun 10;14(6):326. doi: 10.3390/metabo14060326.
4
A Catastrophic Biodiversity Loss in the Environment Is Being Replicated on the Skin Microbiome: Is This a Major Contributor to the Chronic Disease Epidemic?环境中灾难性的生物多样性丧失正在皮肤微生物群中重演:这是慢性病流行的主要原因吗?
Microorganisms. 2023 Nov 16;11(11):2784. doi: 10.3390/microorganisms11112784.
5
Application of the Brazilian patch test panel in the diagnosis of allergic contact dermatitis to cosmetics.巴西斑贴试验面板在化妆品过敏性接触性皮炎诊断中的应用。
An Bras Dermatol. 2022 Sep-Oct;97(5):656-660. doi: 10.1016/j.abd.2021.06.009. Epub 2022 Jun 25.
6
Contact dermatitis: Clinical practice findings from a single tertiary referral hospital, a 4-Year retrospective study.接触性皮炎:来自一家三级转诊医院的临床实践结果,一项为期4年的回顾性研究。
World Allergy Organ J. 2020 Aug 11;13(7):100440. doi: 10.1016/j.waojou.2020.100440. eCollection 2020 Jul.
Multicentre patch testing with methylisothiazolinone by the European Environmental and Contact Dermatitis Research Group.
欧洲环境与接触性皮炎研究小组对甲基异噻唑啉酮进行的多中心斑贴试验。
Contact Dermatitis. 2014 May;70(5):317-20. doi: 10.1111/cod.12220.
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The rise in prevalence of contact allergy to methylisothiazolinone in the British Isles.
Contact Dermatitis. 2014 Apr;70(4):238-40. doi: 10.1111/cod.12185.
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