Puddey I B, Beilin L J, Rakic V
Department of Medicine and Western Australian Heart Research Institute, University of Western Australia, Australia.
Addict Biol. 1997 Apr;2(2):159-70. doi: 10.1080/13556219772705.
Cross-sectional and longitudinal population studies have provided a considerable corpus of evidence for an inverse association between light to moderate alcohol intake and both coronary artery disease and stroke. The formulation of balanced public health advice on the basis of such studies, however, needs to take into account the full spectrum of the effects of alcohol on the cardiovascular system, particularly its equally well documented effect to increase level of blood pressure and prevalence of hypertension. In this review, the broader implications of the association of alcohol with hypertension are discussed, principally in the context of the effect of higher levels of alcohol consumption to increase ischaemic and haemorrhagic stroke, left ventricular hypertrophy, congestive cardiomyopathy, cardiac arrhythmia and sudden cardiac death.
横断面研究和纵向人群研究已经提供了大量证据，表明轻度至中度饮酒与冠状动脉疾病和中风之间存在负相关。然而，基于此类研究制定平衡的公共卫生建议时，需要考虑酒精对心血管系统影响的全貌，尤其是其同样有充分记录的升高血压水平和高血压患病率的作用。在本综述中，将主要在较高酒精摄入量会增加缺血性和出血性中风、左心室肥厚、充血性心肌病、心律失常和心源性猝死风险的背景下讨论酒精与高血压关联的更广泛影响。
