Ogier Stephen E, Wright Steven M
Annu Int Conf IEEE Eng Med Biol Soc. 2015 Aug;2015:1564-7. doi: 10.1109/EMBC.2015.7318671.
Multi-channel receivers are commonplace in MRI, but very few of these receivers are capable of operating over a broad enough bandwidth to accommodate nuclei other than (1)H. While this is fine for imaging, the recent surge in interest in in vivo NMR has created a need for receive arrays to improve the often-poor sensitivity of other nuclei. However, the development of these arrays has been slowed by the scarcity of multi-channel, multinuclear receivers. Frequency translation is a method to solve this by using radiofrequency mixers to convert signals received from multinuclear arrays to the proton frequency, adapting narrow-band receivers to multinuclear use. This method works with a wide variety of nuclei and easily accommodates proton decoupling, a necessity for working with (13)C.
多通道接收器在磁共振成像(MRI)中很常见,但这些接收器中能够在足够宽的带宽上运行以容纳除氢(¹H)以外的原子核的非常少。虽然这对于成像来说没问题,但最近对体内核磁共振(NMR)兴趣的激增产生了对接收阵列的需求,以提高其他原子核通常较差的灵敏度。然而,这些阵列的开发因多通道、多核接收器的稀缺而放缓。频率转换是一种通过使用射频混频器将从多核阵列接收的信号转换为质子频率来解决此问题的方法,使窄带接收器适用于多核应用。这种方法适用于多种原子核,并且很容易实现质子去耦,这是研究碳 - 13(¹³C)时的必要条件。