Sano Yuko, Ichinose Akimichi, Wake Naoki, Osumi Michihiro, Sumitani Masahiko, Kumagaya Shin-Ichiro, Kuniyoshi Yasuo
Annu Int Conf IEEE Eng Med Biol Soc. 2015;2015:2482-5. doi: 10.1109/EMBC.2015.7318897.
The objective of this study is to demonstrate the reliability of relief from phantom limb pain in neurore-habilitation using a multimodal virtual reality system. We have developed a virtual reality rehabilitation system with multimodal sensory feedback and applied it to six patients with brachial plexus avulsion or arm amputation. In an experiment, patients executed a reaching task using a virtual phantom limb displayed in a three-dimensional computer graphic environment manipulated by their real intact limb. The intensity of the phantom limb pain was evaluated through a short-form McGill pain questionnaire. The experiments were conducted twice on different days at more than four-week intervals for each patient. The reliability of our task's ability to relieve pain was demonstrated by the test-retest method, which checks the degree of the relative similarity between the pain reduction rates in two experiments using Fisher's intraclass correlation coefficient (ICC). The ICC was 0.737, indicating sufficient reproducibility of our task. The average of the reduction rates across participants was 50.2%, and it was significantly different from 0 (p <; 0:001). Overall, our findings indicate that neurorehabilitation using our multimodal virtual reality system reduces the phantom limb pain with sufficient reliability.
本研究的目的是证明在神经康复中使用多模态虚拟现实系统缓解幻肢痛的可靠性。我们开发了一种具有多模态感官反馈的虚拟现实康复系统，并将其应用于六名臂丛神经撕脱伤或手臂截肢患者。在一项实验中，患者使用由其真实完好肢体操控的三维计算机图形环境中显示的虚拟幻肢执行伸手任务。通过简短麦吉尔疼痛问卷评估幻肢痛的强度。每个患者在不同日期进行两次实验，间隔超过四周。我们任务缓解疼痛能力的可靠性通过重测法得以证明，该方法使用费希尔组内相关系数（ICC）检查两次实验中疼痛减轻率之间的相对相似程度。ICC为0.737，表明我们的任务具有足够的可重复性。参与者的减轻率平均值为50.2%，且与0有显著差异（p<0.001）。总体而言，我们的研究结果表明，使用我们的多模态虚拟现实系统进行神经康复可充分可靠地减轻幻肢痛。
