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心房颤动期间使用合成心内电图定位螺旋转子源的计算高效方法。

Computationally efficient method for localizing the spiral rotor source using synthetic intracardiac electrograms during atrial fibrillation.

作者信息

Shariat M H, Gazor S, Redfearn D

出版信息

Annu Int Conf IEEE Eng Med Biol Soc. 2015 Aug;2015:4483-6. doi: 10.1109/EMBC.2015.7319390.

DOI:10.1109/EMBC.2015.7319390
PMID:26737290
Abstract

Atrial fibrillation (AF), the most common sustained cardiac arrhythmia, is an extremely costly public health problem. Catheter-based ablation is a common minimally invasive procedure to treat AF. Contemporary mapping methods are highly dependent on the accuracy of anatomic localization of rotor sources within the atria. In this paper, using simulated atrial intracardiac electrograms (IEGMs) during AF, we propose a computationally efficient method for localizing the tip of the electrical rotor with an Archimedean/arithmetic spiral wavefront. The proposed method deploys the locations of electrodes of a catheter and their IEGMs activation times to estimate the unknown parameters of the spiral wavefront including its tip location. The proposed method is able to localize the spiral as soon as the wave hits three electrodes of the catheter. Our simulation results show that the method can efficiently localize the spiral wavefront that rotates either clockwise or counterclockwise.

摘要

心房颤动(AF)是最常见的持续性心律失常,是一个成本极高的公共卫生问题。基于导管的消融是治疗AF的常见微创手术。当代标测方法高度依赖于心房内转子源解剖定位的准确性。在本文中,我们利用房颤期间模拟的心房心内电图(IEGMs),提出了一种计算效率高的方法,用于定位具有阿基米德/算术螺旋波前的电转子尖端。所提出的方法利用导管电极的位置及其IEGMs激活时间来估计螺旋波前的未知参数,包括其尖端位置。该方法能够在波撞击导管的三个电极时立即定位螺旋。我们的模拟结果表明,该方法能够有效地定位顺时针或逆时针旋转的螺旋波前。

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Computationally efficient method for localizing the spiral rotor source using synthetic intracardiac electrograms during atrial fibrillation.心房颤动期间使用合成心内电图定位螺旋转子源的计算高效方法。
Annu Int Conf IEEE Eng Med Biol Soc. 2015 Aug;2015:4483-6. doi: 10.1109/EMBC.2015.7319390.
2
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引用本文的文献

1
Development of a novel probabilistic algorithm for localization of rotors during atrial fibrillation.一种用于心房颤动期间转子定位的新型概率算法的开发。
Annu Int Conf IEEE Eng Med Biol Soc. 2016 Aug;2016:493-496. doi: 10.1109/EMBC.2016.7590747.
2
Anti-arrhythmic strategies for atrial fibrillation: The role of computational modeling in discovery, development, and optimization.心房颤动的抗心律失常策略:计算建模在发现、开发和优化中的作用。
Pharmacol Ther. 2016 Dec;168:126-142. doi: 10.1016/j.pharmthera.2016.09.012. Epub 2016 Sep 6.