D'Ottavio G, Bogatti P, Rustico M A, Mandruzzato G P
Divisione di Ostetricia e Ginecologia, Istituto per l'Infanzia Burlo Garofalo, Trieste, Italia.
Eur J Obstet Gynecol Reprod Biol. 1989 Aug;32(2):79-87. doi: 10.1016/0028-2243(89)90187-1.
In 52 fetuses, in utero sonographic diagnosis of urinary tract malformations was correlated with their autoptic or surgical findings. 39 malformations were correctly diagnosed prenatally, although 5 other extrarenal-associated anomalies were not detected; 10 diagnoses were incomplete; in 3 cases the characteristics of malformations found at sonography turned out to be different at the post-mortem examination. The following factors impaired sonographic diagnoses: limited number of examinations, gestational age at the time of examination, nature of malformation and, above all, oligohydramnios (which is common in most urinary tract malformations). The correlations between renal malformations and karyotype anomalies are also discussed in relation to the higher incidence present in polymalformative syndromes.
对52例胎儿进行了研究,将产前超声诊断的尿路畸形与尸检或手术结果进行了对比。39例畸形在产前得到了正确诊断,不过另外5例肾外相关异常未被检测到;10例诊断不完整;3例超声检查发现的畸形特征在尸检时被证明有所不同。以下因素影响了超声诊断:检查次数有限、检查时的孕周、畸形的性质,最重要的是羊水过少(这在大多数尿路畸形中很常见)。还讨论了肾畸形与核型异常之间的相关性,这与多发畸形综合征中较高的发病率有关。