Wilson R D, Morrison M G, Wittmann B K, Coleman G U
Department of Medical Genetics, University Hospital, Shaughnessy Site, Vancouver, B.C., Canada.
Fetal Ther. 1988;3(3):141-51. doi: 10.1159/000263346.
This retrospective review identified 122 cases with a prenatal diagnosis of genitourinary anomalies and categorized them into parenchymal and collecting system abnormalities. Comparisons were made between the anatomical groups for indications for ultrasound, average gestational age at positive and negative renal ultrasound diagnosis, amniotic fluid volume and pregnancy outcome with postnatal diagnosis. The results indicated that parenchymal abnormalities were detected earlier in gestation than collecting system anomalies. Additional fetal anomalies were more often present in the parenchymal group. Chromosome abnormalities were present in 5% of the urinary tract abnormalities. Parenchymal abnormalities were more likely to have oligohydramnios and a higher morality rate.
这项回顾性研究确定了122例产前诊断为泌尿生殖系统异常的病例,并将其分为实质和集合系统异常。对解剖学分组在超声检查指征、肾脏超声阳性和阴性诊断时的平均孕周、羊水量以及产后诊断的妊娠结局方面进行了比较。结果表明,实质异常在妊娠早期比集合系统异常更早被检测到。实质组中更多见其他胎儿异常。5%的泌尿系统异常存在染色体异常。实质异常更易出现羊水过少且死亡率更高。