Imokawa Shiro, Uehara Masahiro, Uto Tomohiro, Sato Jun, Suda Takafumi
Department of Respiratory Medicine Iwata City Hospital Iwata Japan.
Second Division Department of Internal Medicine Hamamatsu University School of Medicine Hamamatsu Japan.
Respirol Case Rep. 2015 Sep 10;3(4):122-4. doi: 10.1002/rcr2.123. eCollection 2015 Dec.
Organizing pneumonia (OP) is a clinicopathological entity that occurs idiopathically or in association with several conditions, but there are few reports about myeloperoxidase anti-neutrophil cytoplasmic antibody (MPO-ANCA)-associated OP. We describe a patient with OP whose clinical conditions improved spontaneously. Moreover, serum MPO-ANCA titers paralleled the clinical activity of the disease, which disappeared in association with disease quiescence. Based on these findings, a subset of patients may have OP related to MPO-ANCA. ANCA testing should be considered in the work-up of patients with suspected OP.
机化性肺炎（OP）是一种临床病理实体，可自发发生或与多种病症相关，但关于髓过氧化物酶抗中性粒细胞胞浆抗体（MPO-ANCA）相关的OP报道较少。我们描述了一名OP患者，其临床症状自发改善。此外，血清MPO-ANCA滴度与疾病的临床活动平行，随着疾病静止而消失。基于这些发现，一部分患者可能患有与MPO-ANCA相关的OP。对于疑似OP的患者，在检查过程中应考虑进行ANCA检测。
