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立体定向神经外科的未来展望:深部脑肿瘤的立体定向显微手术切除

Future perspectives in stereotactic neurosurgery: stereotactic microsurgical removal of deep brain tumors.

作者信息

Kelly P J

机构信息

Department of Neurosurgery, Mayo Clinic, Rochester.

出版信息

J Neurosurg Sci. 1989 Jan-Mar;33(1):149-54.

PMID:2674348
Abstract

We have developed computer assisted stereotactic methods for the resection of deep seated and centrally located intracranial tumors. Data base acquisition consists of stereotactic computed tomography (CT), magnetic resonance imaging (MRI) and digital angiography (DA). A tumor volume is computer interpolated from CT and MRI defined tumor boundaries. The surgical approach or viewline is selected from stereotactic DA images and anatomically defined by MRI and expressed in mechanical settings on the stereotactic frame. During stereotactic resection the computer displays the position of a stereotactically directed retractor with respect to tumor slices cut perpendicular to the viewline. It is theoretically possible to resect all of the lesion detected by the imaging studies utilizing this method. To date we have performed 267 computer-assisted stereotactic microsurgical resections of a variety of deep seated intracranial tumors with a morbidity rate of 10.5% and mortality rate of 1%. The procedure provides a method by which the surgeon can maintain three dimensional orientation during the resection of CT and MRI defined deep seated intracranial lesions.

摘要

我们已经开发出用于切除深部和位于中枢的颅内肿瘤的计算机辅助立体定向方法。数据库采集包括立体定向计算机断层扫描(CT)、磁共振成像(MRI)和数字血管造影(DA)。肿瘤体积通过计算机从CT和MRI所定义的肿瘤边界进行插值计算。手术入路或视线方向从立体定向DA图像中选择,并通过MRI在解剖学上进行定义,然后在立体定向框架上以机械设置表示。在立体定向切除过程中,计算机显示立体定向导向牵开器相对于垂直于视线方向所切肿瘤切片的位置。从理论上讲,利用这种方法有可能切除影像学检查所发现的所有病变。迄今为止,我们已经对各种深部颅内肿瘤进行了267例计算机辅助立体定向显微手术切除,发病率为10.5%,死亡率为1%。该手术提供了一种方法,通过它外科医生在切除CT和MRI所定义的深部颅内病变时能够保持三维定向。

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