Zivot M L, Kanat I O
J Am Podiatr Med Assoc. 1989 Sep;79(9):421-31. doi: 10.7547/87507315-79-9-421.
Malignant melanoma, the leading cause of death from disease of the skin, often is found on the lower extremity. A thorough understanding of the disease entity is essential, because misdiagnosis or delayed diagnosis can be fatal. In Part I of this two-part clinical and surgical review of malignant melanoma, the authors discussed etiology, risk factors, signs, symptoms, clinical features, and growth patterns. Part II places special emphasis on diagnosing malignant melanoma and differentiating it from other lesions of the lower extremity. Clinical staging of the tumor and the corresponding surgical criteria are presented from a podiatric medical standpoint.
恶性黑色素瘤是皮肤疾病致死的主要原因,常发生于下肢。对该疾病实体有透彻的了解至关重要,因为误诊或延迟诊断可能是致命的。在这篇关于恶性黑色素瘤的两部分临床与外科综述的第一部分中,作者讨论了病因、危险因素、体征、症状、临床特征和生长模式。第二部分特别强调了恶性黑色素瘤的诊断以及将其与下肢其他病变相鉴别。从足病医学的角度介绍了肿瘤的临床分期及相应的手术标准。