Le Guyader Maïlys, Pineau-Vincent Fabienne, Lemaire Pierre
Laboratoire d'hématologie et immunologie, Centre Hospitalier, Le Mans, France.
Ann Biol Clin (Paris). 2016 Jan-Feb;74(1):106-9. doi: 10.1684/abc.2015.1117.
Paroxysmal nocturnal hemoglobinuria is a rare clonal non-malignant disease, linked to an acquired PIG-A gene mutation. We report the case of 81 years old patient hospitalized for articular ache, swelling and temporal arteries' induration in which we diagnose PNH associated with refractory cytopenia with multilineage dysplasia.
阵发性睡眠性血红蛋白尿症是一种罕见的克隆性非恶性疾病，与获得性PIG-A基因突变有关。我们报告了一例81岁患者，因关节疼痛、肿胀和颞动脉硬结入院，经诊断为阵发性睡眠性血红蛋白尿症合并难治性全血细胞减少伴多系发育异常。
