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Regulation of K+ channels plays a crucial role in the control of insulin secretion.

作者信息

Petersen O H, Dunne M J

机构信息

MRC Secretory Control Research Group, Physiological Laboratory, University of Liverpool, Great Britain.

出版信息

Pflugers Arch. 1989;414 Suppl 1:S115-20. doi: 10.1007/BF00582259.

DOI:10.1007/BF00582259
PMID:2674891
Abstract
摘要

相似文献

1
Regulation of K+ channels plays a crucial role in the control of insulin secretion.钾离子通道的调节在胰岛素分泌的控制中起着至关重要的作用。
Pflugers Arch. 1989;414 Suppl 1:S115-20. doi: 10.1007/BF00582259.
2
ATP-sensitive K+ channels: a link between B-cell metabolism and insulin secretion.
Biochem Soc Trans. 1990 Feb;18(1):109-11. doi: 10.1042/bst0180109.
3
Ion channels and the molecular control of insulin secretion.离子通道与胰岛素分泌的分子调控
Biochem Soc Trans. 1994 Feb;22(1):6-12. doi: 10.1042/bst0220006.
4
Heterogeneity of beta-cell secretion. Possible involvement of K-ATP channels.
Adv Exp Med Biol. 1997;426:247-52.
5
[Ion channel mechanisms in insulin secretion].
Nihon Rinsho. 2002 Jul;60 Suppl 7:180-9.
6
Members of the Kv1 and Kv2 voltage-dependent K(+) channel families regulate insulin secretion.Kv1和Kv2电压依赖性钾离子通道家族的成员调节胰岛素分泌。
Mol Endocrinol. 2001 Aug;15(8):1423-35. doi: 10.1210/mend.15.8.0685.
7
Blockade of K+ channels in insulin-secreting cells by the 'potassium channel opener' SDZ PCO 400.“钾通道开放剂”SDZ PCO 400对胰岛素分泌细胞中钾通道的阻断作用
Biochem Soc Trans. 1993 Nov;21(4):402S. doi: 10.1042/bst021402s.
8
[Regulation of potassium channels in insulin secreting cells].[胰岛素分泌细胞中钾通道的调节]
Arzneimittelforschung. 1989 Jan;39(1A):181-5.
9
Regulation of insulin secretion via ATP-sensitive K+ channel independent mechanisms: role of phospholipase C.通过ATP敏感性钾通道非依赖机制对胰岛素分泌的调节：磷脂酶C的作用
Am J Physiol. 1997 Apr;272(4 Pt 1):E671-7. doi: 10.1152/ajpendo.1997.272.4.E671.
10
Role of potassium channels in the modulation of insulin release.钾通道在胰岛素释放调节中的作用。
Diabetologia. 1996 Jul;39(7):865-7. doi: 10.1007/s001250050523.

引用本文的文献

1
Cibenzoline inhibits diazoxide- and 2,4-dinitrophenol-activated ATP-sensitive K+ channels in guinea-pig ventricular cells.西苯唑啉抑制豚鼠心室细胞中由二氮嗪和2,4-二硝基苯酚激活的ATP敏感性钾通道。
Br J Pharmacol. 1993 Feb;108(2):549-56. doi: 10.1111/j.1476-5381.1993.tb12839.x.
2
Essential role of adenosine, adenosine A1 receptors, and ATP-sensitive K+ channels in cerebral ischemic preconditioning.腺苷、腺苷A1受体和ATP敏感性钾通道在脑缺血预处理中的重要作用。
Proc Natl Acad Sci U S A. 1995 May 9;92(10):4666-70. doi: 10.1073/pnas.92.10.4666.
3
Glucose modulates rat substantia nigra GABA release in vivo via ATP-sensitive potassium channels.

本文引用的文献

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Replacement of the protoplasm of a giant nerve fibre with artificial solutions.用人造溶液替代巨型神经纤维的原生质。
Nature. 1961 Jun 3;190:885-7. doi: 10.1038/190885a0.
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Calcium-activated potassium channels and their role in secretion.钙激活钾通道及其在分泌中的作用。
Nature. 1984;307(5953):693-6. doi: 10.1038/307693a0.
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Regulation of insulin release by calcium.钙对胰岛素释放的调节。
葡萄糖通过ATP敏感性钾通道在体内调节大鼠黑质γ-氨基丁酸的释放。
J Clin Invest. 1995 May;95(5):2403-8. doi: 10.1172/JCI117935.
4
Vasopressin directly closes ATP-sensitive potassium channels evoking membrane depolarization and an increase in the free intracellular Ca2+ concentration in insulin-secreting cells.血管加压素直接关闭ATP敏感性钾通道，引起膜去极化，并使胰岛素分泌细胞内的游离Ca2+浓度升高。
EMBO J. 1989 Dec 1;8(12):3595-9. doi: 10.1002/j.1460-2075.1989.tb08532.x.
5
The effects of cromakalim on ATP-sensitive potassium channels in insulin-secreting cells.克罗卡林对胰岛素分泌细胞中ATP敏感性钾通道的作用。
Br J Pharmacol. 1990 Jan;99(1):169-75. doi: 10.1111/j.1476-5381.1990.tb14672.x.
6
Comparative study of the effects of cromakalim (BRL 34915) and diazoxide on membrane potential, [Ca2+]i and ATP-sensitive potassium currents in insulin-secreting cells.克罗卡林（BRL 34915）和二氮嗪对胰岛素分泌细胞的膜电位、细胞内钙离子浓度（[Ca2+]i）及ATP敏感性钾电流影响的比较研究
J Membr Biol. 1990 Mar;114(1):53-60. doi: 10.1007/BF01869384.
7
Effects of pinacidil, RP 49356 and nicorandil on ATP-sensitive potassium channels in insulin-secreting cells.吡那地尔、RP 49356和尼可地尔对胰岛素分泌细胞中ATP敏感性钾通道的影响。
Br J Pharmacol. 1990 Mar;99(3):487-92. doi: 10.1111/j.1476-5381.1990.tb12955.x.
8
ATP-dependent potassium channels of muscle cells: their properties, regulation, and possible functions.
J Bioenerg Biomembr. 1991 Aug;23(4):509-35. doi: 10.1007/BF00785809.
9
Block of ATP-regulated potassium channels by phentolamine and other alpha-adrenoceptor antagonists.酚妥拉明及其他α-肾上腺素能受体拮抗剂对ATP调节钾通道的阻断作用
Br J Pharmacol. 1991 Aug;103(4):1847-50. doi: 10.1111/j.1476-5381.1991.tb12340.x.
Physiol Rev. 1981 Oct;61(4):914-73. doi: 10.1152/physrev.1981.61.4.914.
4
Glucose induces closure of single potassium channels in isolated rat pancreatic beta-cells.葡萄糖可诱导分离的大鼠胰腺β细胞中的单个钾通道关闭。
Nature. 1984;312(5993):446-8. doi: 10.1038/312446a0.
5
Electrical activity in pancreatic islet cells.胰岛细胞中的电活动。
Nature. 1968 Jul 27;219(5152):389-90. doi: 10.1038/219389a0.
6
Structure of the voltage-dependent potassium channel is highly conserved from Drosophila to vertebrate central nervous systems.电压依赖性钾通道的结构从果蝇到脊椎动物中枢神经系统都高度保守。
EMBO J. 1988 Aug;7(8):2457-63. doi: 10.1002/j.1460-2075.1988.tb03092.x.
7
The gating of nucleotide-sensitive K+ channels in insulin-secreting cells can be modulated by changes in the ratio ATP4-/ADP3- and by nonhydrolyzable derivatives of both ATP and ADP.胰岛素分泌细胞中核苷酸敏感性钾通道的门控可通过ATP4⁻/ADP3⁻比值的变化以及ATP和ADP的不可水解衍生物来调节。
J Membr Biol. 1988 Sep;104(2):165-77. doi: 10.1007/BF01870928.
8
Activators of protein kinase C depolarize insulin-secreting cells by closing K+ channels.蛋白激酶C激活剂通过关闭钾离子通道使胰岛素分泌细胞去极化。
EMBO J. 1988 Aug;7(8):2443-9. doi: 10.1002/j.1460-2075.1988.tb03090.x.
9
Cytosolic ADP enhances the sensitivity to tolbutamide of ATP-dependent K+ channels from pancreatic B-cells.胞质中的二磷酸腺苷（ADP）增强了胰腺β细胞中ATP依赖性钾通道对甲苯磺丁脲的敏感性。
FEBS Lett. 1988 Nov 7;239(2):241-4. doi: 10.1016/0014-5793(88)80925-6.
10
Effects of pyridine nucleotides on the gating of ATP-sensitive potassium channels in insulin-secreting cells.
J Membr Biol. 1988 Jun;102(3):205-16. doi: 10.1007/BF01925714.