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咽瓣是否会限制腭裂患者早期面中部的生长?

Do Pharyngeal Flaps Restrict Early Midface Growth in Patients With Clefts?

作者信息

Jones Christine M, Mackay Andrew F J, Mackay Donald R, Long Ross E

出版信息

Cleft Palate Craniofac J. 2016 Nov;53(6):629-633. doi: 10.1597/15-149. Epub 2016 Jan 11.

DOI:10.1597/15-149
PMID:26752133
Abstract

OBJECTIVE

To compare facial growth characteristics in patients with cleft palate who have undergone pharyngeal flap with those who had palatal lengthening or pharyngoplasty and to control subjects who have not had surgery for velopharyngeal insufficiency (VPI).

DESIGN

Matched retrospective cohort study.

SETTING

Multidisciplinary cleft care center.

PATIENTS

All patients with cleft palate who had undergone pharyngeal flap or pharyngoplasty/palatal lengthening for VPI were included. Patients with craniofacial syndromes or those who had undergone maxillary protraction were excluded. A control group did not undergo surgery for VPI. The three groups were matched based on cleft type and ages at VPI surgery and cephalogram.

MAIN OUTCOME MEASURES

Thirteen craniofacial measurements were evaluated on postoperative cephalograms using an analysis of variance with a Bonferroni adjustment for significant measures (α = 0.05).

RESULTS

Seventy-two patients were included; mean ages at VPI surgery and postoperative cephalogram were 5 and 8 years, respectively. Twelve of thirteen craniofacial measures were not significantly different; notably, this included maxillary height and projection. Only gonial angle was found to differ significantly (P = .018) in that pharyngoplasty and pharyngeal flap yielded a smaller angle compared with that in control subjects.

CONCLUSION

Facial growth, and in particular maxillary growth, was not altered as expected after pharyngeal flap surgery. Pharyngeal flap appears to be equivalent to pharyngoplasty and palatal lengthening in that no significant effects on early facial growth were detected after surgery for VPI in this cohort of children with cleft palate.

摘要

目的

比较接受咽瓣手术的腭裂患者与接受腭延长术或咽成形术的患者以及未因腭咽闭合不全(VPI)接受手术的对照受试者的面部生长特征。

设计

匹配的回顾性队列研究。

地点

多学科腭裂护理中心。

患者

纳入所有因VPI接受咽瓣手术或咽成形术/腭延长术的腭裂患者。排除患有颅面综合征或接受过上颌前牵引的患者。对照组未因VPI接受手术。三组根据腭裂类型、VPI手术时的年龄和头颅侧位片进行匹配。

主要观察指标

在术后头颅侧位片上评估13项颅面测量指标,采用方差分析,并对显著测量指标进行Bonferroni校正(α = 0.05)。

结果

纳入72例患者;VPI手术时的平均年龄和术后头颅侧位片时的平均年龄分别为5岁和8岁。13项颅面测量指标中的12项无显著差异;值得注意的是,这包括上颌高度和突出度。仅发现下颌角有显著差异(P = 0.018),即咽成形术和咽瓣手术组的下颌角比对照组小。

结论

咽瓣手术后面部生长,尤其是上颌生长,并未如预期那样改变。在这组腭裂儿童中,对于VPI手术后的早期面部生长,咽瓣手术似乎与咽成形术和腭延长术等效,未检测到显著影响。

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