Serradimigni A, Jouve R, Gilgenkrantz J M
Therapie. 1989 May-Jun;44(3):155-9.
Calcium-entry blockers are the drugs of choice in coronary spasm, unstable angina, and when patients do not have any effort limitation. However, beta-blockers, without sympathomimetic activity, remain the treatment of angina pectoris. When clinical situation is difficult to control, association calcium blockers and bêta-blockers are more efficient than monotherapy. In myocardial infarction, results are controversial: calcium channel blockers should be administered only with beta-blockers.
钙通道阻滞剂是治疗冠状动脉痉挛、不稳定型心绞痛以及无运动耐量受限患者的首选药物。然而,无拟交感活性的β受体阻滞剂仍是心绞痛的治疗药物。当临床情况难以控制时,联合使用钙通道阻滞剂和β受体阻滞剂比单一疗法更有效。在心肌梗死中,结果存在争议:钙通道阻滞剂应仅与β受体阻滞剂联合使用。