Asselmann Eva, Hoyer Jurgen, Wittchen Hans-Ulrich, Martini Julia
Institute of Clinical Psychology and Psychotherapy, Technische Universität Dresden, Dresden, Germany; Behavioral Epidemiology, Technische Universität Dresden, Dresden, Germany.
Institute of Clinical Psychology and Psychotherapy, Technische Universität Dresden, Dresden, Germany.
J Sex Med. 2016 Jan;13(1):95-104. doi: 10.1016/j.jsxm.2015.12.005.
Few prospective-longitudinal studies have examined the course of sexual problems during pregnancy and after delivery in women with and without anxiety and depressive disorders prior to pregnancy as well as with and without maternal birth injuries.
To prospectively investigate associations of anxiety and depressive disorders prior to pregnancy and maternal birth injuries with sexual problems during the peripartum period.
The Maternal Anxiety in Relation to Infant Development Study is a prospective-longitudinal study of 306 women enrolled during early pregnancy and repeatedly assessed in seven waves during the peripartum period. Anxiety and depressive disorders prior to pregnancy were assessed in early pregnancy (T1) using the Composite International Diagnostic Interview for Women. Maternal birth injuries were assessed by questionnaire shortly after delivery (T4). Sexual problems during pregnancy (T2) as well as 4 months (T6) and 16 months (T7) postpartum were measured using the German version of the Massachusetts General Hospital Sexual Function Questionnaire.
Impairment of sexual interest, arousal, orgasm, lubrication, and overall sexual satisfaction at T2, T6, and T7.
Rates of sexual problems generally increased from T2 to T6 and decreased from T6 to T7. Compared with women without anxiety and depressive disorders, those with comorbid anxiety and depressive disorders prior to pregnancy more often specified impairment of overall sexual satisfaction at T2 (odds ratio [OR] = 2.0) and T7 (OR = 2.1). In contrast, sexual problems were not pronounced in those with pure anxiety or pure depressive disorders, and women with pure anxiety disorders often reported even less impairment of sexual interest at T7 (OR = 0.5). Compared with women without birth injury, those with vaginal birth injury more often reported impairment of sexual interest (OR = 1.8) and lubrication (OR = 2.3) at T6.
Findings suggest that especially women with comorbid anxiety and depression and vaginal birth injury are at increased risk for sexual problems during pregnancy and after delivery and thus might benefit from targeted early interventions.
很少有前瞻性纵向研究探讨过,孕期及产后有或没有焦虑和抑郁障碍、有或没有母体分娩损伤的女性的性问题发展过程。
前瞻性调查孕期前的焦虑和抑郁障碍以及母体分娩损伤与围产期性问题之间的关联。
母婴焦虑与婴儿发育关系研究是一项前瞻性纵向研究,对306名在孕早期入组的女性进行研究,并在围产期分七波进行反复评估。孕早期(T1)使用妇女综合国际诊断访谈评估孕期前的焦虑和抑郁障碍。产后不久(T4)通过问卷评估母体分娩损伤。孕期(T2)以及产后4个月(T6)和16个月(T7)的性问题使用德文版的马萨诸塞州综合医院性功能问卷进行测量。
T2、T6和T7时性兴趣、性唤起、性高潮、润滑和总体性满意度的受损情况。
性问题发生率通常从T2到T6上升,从T6到T7下降。与没有焦虑和抑郁障碍的女性相比,孕期前患有共病焦虑和抑郁障碍的女性在T2(优势比[OR]=2.0)和T7(OR=2.1)时更常出现总体性满意度受损。相比之下,单纯焦虑或单纯抑郁障碍患者的性问题并不明显,患有单纯焦虑障碍的女性在T7时性兴趣受损情况甚至更少(OR=0.5)。与没有分娩损伤的女性相比,有阴道分娩损伤的女性在T6时更常出现性兴趣(OR=1.8)和润滑(OR=2.3)受损。
研究结果表明,尤其是患有共病焦虑和抑郁以及有阴道分娩损伤的女性在孕期及产后出现性问题的风险增加,因此可能受益于有针对性的早期干预。