Perkins A C, Richards V L, Gibson J, Joshua D E, Johnson J R, Kronenberg H
Haematology Department, Royal Prince Alfred Hospital, Camperdown, NSW, Australia.
Aust N Z J Med. 1989 Aug;19(4):345-6. doi: 10.1111/j.1445-5994.1989.tb00275.x.
We describe a case of immune hemolysis due to anti-B occurring in a blood group B patient 16 days after a cadaveric renal transplantation from a blood group O donor. Transfusional support was initially required and the direct antiglobulin test (DAT) remained positive for 80 days. Cyclosporin A (CSA), which was used for rejection prophylaxis in this case, has unique immunosuppressive capabilities which protects transplanted organs from rejection, but which might permit this type of 'graft versus host' reaction.
