Kashyap Namrata, Pradhan Mandakini, Singh Neeta, Yadav Sangeeta
Department of Maternal and Reproductive Health, Sanjay Gandhi Post Graduate Institute of Medical Sciences (SGPGIMS), Lucknow 226 014, India.
J Pregnancy. 2015;2015:623059. doi: 10.1155/2015/623059. Epub 2015 Nov 23.
Early detection of malformation is tremendously improved with improvement in imaging technology. Yet in a developing country like India majority of pregnant women are not privileged to get timely diagnosis.
To assess the present status and potential of first trimester ultrasonography in detection of fetal congenital structural malformations.
This was a retrospective observational study conducted at Sanjay Gandhi Postgraduate Institute of Medical Sciences. All pregnant women had anomaly scan and women with fetal structural malformations were included.
Out of 4080 pregnant women undergoing ultrasound, 312 (7.6%) had fetal structural malformation. Out of 139 patients who were diagnosed after 20 weeks, 47 (33.8%) had fetal structural anomalies which could have been diagnosed before 12 weeks and 92 (66.1%) had fetal malformations which could have been diagnosed between 12 and 20 weeks.
The first trimester ultrasonography could have identified 50% of major structural defects compared to 1.6% in the present scenario. This focuses on the immense need of the hour to gear up for early diagnosis and timely intervention in the field of prenatal detection of congenital malformation.
随着成像技术的进步，畸形的早期检测有了极大改善。然而在像印度这样的发展中国家，大多数孕妇无法获得及时诊断。
评估孕早期超声检查在检测胎儿先天性结构畸形方面的现状和潜力。
这是一项在桑贾伊·甘地医学科学研究生学院进行的回顾性观察研究。所有孕妇均进行了畸形扫描，纳入有胎儿结构畸形的女性。
在4080名接受超声检查的孕妇中，312名（7.6%）有胎儿结构畸形。在20周后确诊的139名患者中，47名（33.8%）有在12周前本可诊断出的胎儿结构异常，92名（66.1%）有在12至20周之间本可诊断出的胎儿畸形。
与目前情况下的1.6%相比，孕早期超声检查本可识别50%的主要结构缺陷。这突出了当下在先天性畸形产前检测领域加紧进行早期诊断和及时干预的迫切需求。
