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Transient cyclic neutropenia following GM-CSF in a patient with chronic granulocytic leukemia transplanted with HLA-identical T cell-depleted donor bone marrow.

作者信息

Gluckman E, Socie G, Yver A, Esperou H, Devergie A, Stern A

机构信息

Bone Marrow Transplant Unit, Hôpital Saint Louis, Paris, France.

出版信息

Bone Marrow Transplant. 1989 Sep;4(5):591-2.

PMID:2676045
Abstract

Treatment with GM-CSF or G-CSF is becoming widely used in patients with chronic neutropenia, or who are aplastic following chemotherapy or autologous or allogeneic bone marrow transplantation. Recently, some authors have described a phenomenon analogous to cyclic agranulocytosis following treatment with G-CSF in a patient with chronic neutropenia. We wish to describe the same phenomenon in a patient with chronic granulocytic leukemia who received GM-CSF (Sandoz) after T cell depletion in order to accelerate hematological reconstitution.

摘要

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