Ware Lisa J, Rennie Kirsten L, Gafane Lebo F, Nell Tarryn M, Thompson Jane E S, Van Rooyen Johannes M, Schutte Rudolph, Schutte Aletta E
Hypertension in Africa Research Team (HART), North-West University, Potchefstroom, South Africa.
Centre for Lifespan and Chronic Illness Research, University of Hertfordshire, Hertfordshire, UK.
J Clin Hypertens (Greenwich). 2016 May;18(5):396-404. doi: 10.1111/jch.12768. Epub 2016 Jan 13.
While South Africa has one of the highest hypertension rates globally, there are few data on masked hypertension (MHT) and white-coat hypertension (WCHT). This study measured the frequency of MHT and WCHT in low-income (<$500 US per month) South African adults, evaluating cardiovascular risk by arterial stiffness. Participants (n=101, 50% male; mean age 39.4±9.7 years) were recruited from a large North-West Province employer. Clinic and 24-hour blood pressure (BP) and pulse wave analysis were recorded. Clinic BP identified 18% of patients as hypertensive, while 24-hour BP showed that 63% of patients were hypertensive. The frequency of MHT was high (33 of 81, 41%) with only one case of WCHT. In comparison to those with normal clinic and 24-hour BP, augmentation index and pulse wave velocity were significantly higher in those with hypertensive 24-hour BP irrespective of clinic BP, indicating that, in this group, masked and sustained hypertension carry a similar elevated cardiovascular risk.
虽然南非是全球高血压发病率最高的国家之一,但关于隐蔽性高血压(MHT)和白大衣高血压(WCHT)的数据却很少。本研究测量了低收入(每月低于500美元)南非成年人中MHT和WCHT的发生率,并通过动脉僵硬度评估心血管风险。参与者(n = 101,50%为男性;平均年龄39.4±9.7岁)来自西北省的一家大型雇主单位。记录了诊所血压和24小时血压(BP)以及脉搏波分析结果。诊所血压显示18%的患者为高血压患者,而24小时血压显示63%的患者为高血压患者。MHT的发生率很高(81例中有33例,占41%),只有1例WCHT。与诊所血压和24小时血压均正常的患者相比,24小时血压为高血压的患者,无论诊所血压如何,其增强指数和脉搏波速度均显著更高,这表明在该组中,隐蔽性高血压和持续性高血压具有相似的升高的心血管风险。