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成人双侧隐睾症的后果。

Consequences of bilateral cryptorchidism in adults.

作者信息

Adomaitis R, Vincel B, Eidukaite A, Ostaneviciute E, Kirka R, Bilius V, Malcius D, Verkauskas G, Hadziselimovic F

机构信息

Centre of Urology, Faculty of Medicine, Vilnius University, Vilnius, Lithuania.

Children's Surgery Centre, Faculty of Medicine, Vilnius University, Vilnius, Lithuania.

出版信息

Andrologia. 2016 Nov;48(9):933-938. doi: 10.1111/and.12534. Epub 2016 Jan 14.

DOI:10.1111/and.12534
PMID:26762811
Abstract

Bilateral cryptorchidism treatment results are often shadowed by the majority of unilateral cases. We report the long-term follow-up results of boys treated for bilateral cryptorchidism during childhood. Patients treated in two main paediatric surgery centres were selected from medical registries and invited for a clinical examination including scrotal ultrasound, salivary testosterone measurement and a semen sample. Thirty-six men (38.3%) replied to the written invitation, and 21 agreed to be examined. The mean age at orchidopexy was 74 months (range 24-138). Sperm count was 0.42 × 10 (SD ± 0.64 × 10 ) ml . The correlation between total testicular volume and total sperm count was statistically significant (r = 0.481; P = 0.032). These results show that surgical treatment of bilateral cryptorchidism after the age of 2 years does not prevent infertility. Sperm count and endocrine evaluation advocated after the treatment of bilateral cryptorchidism in all adult patients.

摘要

双侧隐睾症的治疗结果常常被大多数单侧病例所掩盖。我们报告了儿童期接受双侧隐睾症治疗的男孩的长期随访结果。从医疗登记处选取了在两个主要儿科手术中心接受治疗的患者,并邀请他们进行临床检查,包括阴囊超声、唾液睾酮测量和精液样本采集。36名男性(38.3%)回复了书面邀请,21人同意接受检查。睾丸固定术时的平均年龄为74个月(范围24 - 138个月)。精子计数为0.42×10(标准差±0.64×10)/毫升。总睾丸体积与总精子计数之间的相关性具有统计学意义(r = 0.481;P = 0.032)。这些结果表明,2岁以后对双侧隐睾症进行手术治疗并不能预防不育症。建议对所有成年双侧隐睾症患者在治疗后进行精子计数和内分泌评估。

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1
Consequences of bilateral cryptorchidism in adults.成人双侧隐睾症的后果。
Andrologia. 2016 Nov;48(9):933-938. doi: 10.1111/and.12534. Epub 2016 Jan 14.
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Undescended testis histology correlation with adult hormone levels and semen analysis.隐睾症组织学与成人激素水平和精液分析的相关性。
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Testicular histology related to fertility outcome and postpubertal hormone status in cryptorchidism.隐睾症中与生育结局及青春期后激素状态相关的睾丸组织学
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Cryptorchidism: aspects of fertility and neoplasms. A study including data of 1,335 consecutive boys who underwent testicular biopsy simultaneously with surgery for cryptorchidism.隐睾症:生育力与肿瘤方面。一项研究纳入了1335名连续接受隐睾症手术同时进行睾丸活检的男孩的数据。
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Semen analysis of patients who had orchidopexy at or after seven years of age.对7岁及7岁以后接受睾丸固定术的患者进行精液分析。
Lancet. 1988 Nov 5;2(8619):1051-2. doi: 10.1016/s0140-6736(88)90067-0.
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Asian J Androl. 2022 Sep-Oct;24(5):500-502. doi: 10.4103/aja202227.
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Hypogonadism and Cryptorchidism.性腺功能减退和隐睾症。
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