Suppr超能文献

经导管与手术关闭儿童房间隔缺损:价值比较。

Transcatheter Versus Surgical Closure of Atrial Septal Defects in Children: A Value Comparison.

机构信息

Division of Cardiology, Children's Healthcare of Atlanta, Atlanta, Georgia; Department of Pediatrics, Emory University School of Medicine, Atlanta, Georgia.

Department of Pediatrics, Emory University School of Medicine, Atlanta, Georgia.

出版信息

JACC Cardiovasc Interv. 2016 Jan 11;9(1):79-86. doi: 10.1016/j.jcin.2015.09.028.

Abstract

OBJECTIVES

The purpose of this study was to determine whether a transcatheter procedure or surgical closure offers a better value proposition for atrial septal defect (ASD) closure.

BACKGROUND

Secundum ASDs are common congenital heart defects with both transcatheter and surgical treatment options. Although both options have been shown to have excellent results in children, the relative value of the 2 procedures is unclear.

METHODS

Using data from the Pediatric Hospital Information System for 2004 to 2012, we compared the value of transcatheter versus surgical ASD closure for children ages 1 to 17 years, with value being defined as outcomes relative to costs. Total charges for procedure-related encounters were converted to costs using hospital-specific cost-to-charge ratios, and all costs were adjusted for inflation to reflect 2012 dollars.

RESULTS

There were 4,606 transcatheter procedures and 3,159 surgeries at 35 children's hospitals. Those undergoing transcatheter closure were more likely to be older (5.6 years vs. 4.5 years, p < 0.0001). There was no mortality in either group. Children with a surgical procedure had a longer length of stay (4.0 days vs. 1.5 days, p < 0.0001), were more likely to have an infection (odds ratio: 3.73, p < 0.0001) or procedural complication (odds ratio: 6.66, p < 0.0001). Costs for transcatheter procedure encounters were lower than costs for surgical encounters (mean of $19,128 vs. $25,359, p < 0.0001).

CONCLUSIONS

Both transcatheter and surgical ASD closure had excellent short-term outcomes, but transcatheter procedures had lower lengths of stay, rates of infection, and complications, resulting in lower overall costs. For children who are eligible, transcatheter ASD closure provides better short-term value than surgery.

摘要

目的

本研究旨在确定经导管介入治疗与手术修复治疗房间隔缺损(ASD),哪种方案更具成本效益。

背景

继发孔型 ASD 是常见的先天性心脏病,有经导管介入治疗和手术治疗两种选择。虽然两种方法在儿童中均取得了良好的效果,但两种治疗方案的相对价值尚不清楚。

方法

利用 2004 年至 2012 年小儿医院信息系统的数据,我们比较了年龄在 1 至 17 岁的儿童行经导管介入治疗与手术修复治疗 ASD 的价值,价值定义为治疗效果与治疗费用的比值。通过医院特定的成本与收费比率将与手术相关的费用转换为成本,并对所有费用进行通货膨胀调整,以反映 2012 年的美元价值。

结果

35 家儿童医院共开展了 4606 例经导管介入治疗和 3159 例手术。接受经导管介入治疗的患者年龄更大(5.6 岁 vs. 4.5 岁,p<0.0001)。两组均无死亡病例。手术组的住院时间更长(4.0 天 vs. 1.5 天,p<0.0001),感染(比值比:3.73,p<0.0001)或手术并发症(比值比:6.66,p<0.0001)的发生率更高。经导管介入治疗的费用低于手术治疗(平均费用分别为 19128 美元和 25359 美元,p<0.0001)。

结论

经导管介入治疗与手术修复治疗 ASD 的短期效果均良好,但经导管介入治疗的住院时间更短,感染和并发症的发生率更低,从而导致总费用更低。对于符合条件的患者,经导管 ASD 修复术的短期价值优于手术修复术。

文献AI研究员

20分钟写一篇综述,助力文献阅读效率提升50倍。

立即体验

用中文搜PubMed

大模型驱动的PubMed中文搜索引擎

马上搜索

文档翻译

学术文献翻译模型,支持多种主流文档格式。

立即体验