Nolte A, Strube C, Raue K, Brämer C, Baumgärtner W, Wohlsein P
Dr. Peter Wohlsein, Institut für Pathologie, Tierärztliche Hochschule Hannover, Bünteweg 17, 30559 Hannover, E-Mail:
Tierarztl Prax Ausg K Kleintiere Heimtiere. 2016;44(1):53-8. doi: 10.15654/TPK-150145. Epub 2016 Jan 14.
A male, 12-year-old Cairn terrier suffering from Cushing's syndrome with two therapy-resistant inflammatory subcutaneous lesions was examined pathomorphologically and parasitologically. Within the subcutaneous tissue, there was a suppurative to necrotizing and histiocytic inflammation present with the formation of caverns. Intralesional whitish-grey cysts with a diameter of 1-4 mm were detected. Molecular investigations of the cysts confirmed the preliminary morphological identification as Cysticercus longicollis. The adenohypophysis showed an infiltrative growing carcinoma. Cysticercus longicollis is the metacestode of Taenia (T.) crassiceps, a tapeworm of foxes and coyotes. Small rodents are typical intermediate hosts, in which the metacestode develops within the body cavities as well as in the subcutis. Subcutaneous cysticercosis after infection with eggs of T. crassiceps is also described in different domestic animal species and in humans, who represent aberrant intermediate hosts. Immunosuppression due to Cushing's syndrome, probably caused by the tumor of the adenohypophysis, may have played a role in the pathogenesis of the present case.
一只12岁的雄性凯恩梗犬患有库欣综合征，伴有两处对治疗有抵抗性的炎性皮下病变，对其进行了病理形态学和寄生虫学检查。在皮下组织内，存在化脓性至坏死性及组织细胞性炎症，并形成空洞。在病变内检测到直径为1 - 4毫米的灰白色囊肿。对囊肿的分子研究证实了初步的形态学鉴定结果为长囊尾蚴。腺垂体显示为浸润性生长的癌。长囊尾蚴是狐狸和郊狼的绦虫——粗颈带绦虫（Taenia (T.) crassiceps）的中绦期幼虫。小型啮齿动物是典型的中间宿主，中绦期幼虫在其体腔以及皮下组织内发育。不同家畜物种和作为异常中间宿主的人类感染粗颈带绦虫卵后的皮下囊尾蚴病也有相关描述。库欣综合征导致的免疫抑制，可能是由腺垂体肿瘤引起的，在本病例的发病机制中可能起到了作用。
