Lim C-W, Lee J-H, Im S-M, Song I-K, Park H-P, Kim H-S, Kim J-T
Department of Anesthesiology and Pain Medicine, Seoul National University Hospital, Seoul, Korea.
Acta Anaesthesiol Scand. 2016 Apr;60(4):432-40. doi: 10.1111/aas.12683. Epub 2016 Jan 13.
The purpose of this study was to determine causes and characteristics of early postoperative mortality focusing on postoperative day 1 (POD 1).
We reviewed the electronic medical records of patients who died within 7 days after surgery under anesthesia at a tertiary university hospital from January 2004 to December 2014. Postoperative mortalities were divided into POD 1 group and POD 7 group, which included death that occurred from days 2 to 7 after surgery. Characteristics of POD 1 group were compared with those of POD 7 group.
The mortality rates of POD 1 and POD 7 groups were 3.6 and 7.8 per 10,000 anesthesia, respectively. The incidence of POD 1 mortality is higher than any other day of the week of surgery. The incidences of massive transfusion, intraoperative cardiac arrest, and intraoperative use of epinephrine were higher in POD 1 group than in POD 7 group. In adults, the proportion of emergency operations was higher in POD 1 group than in POD 7 group. The leading cause of death in POD 1 group was hypovolemic and cardiogenic shock, whereas that in POD 7 group was distributive shock. Human factor-related mortality was more frequent in POD 1 group (15.3%) compared with POD 7 group (6.1%).
The characteristics of POD 1 mortality were different from those of POD 2-7 mortality. A large proportion of early postoperative deaths were due to POD 1 mortality. Human factor-related causes were more associated with POD 1 mortality, indicating much room for improvement.
本研究的目的是确定术后早期死亡的原因和特征,重点关注术后第1天(POD 1)。
我们回顾了2004年1月至2014年12月在一所三级大学医院接受麻醉手术后7天内死亡患者的电子病历。术后死亡分为POD 1组和POD 7组,POD 7组包括术后第2天至第7天发生的死亡。将POD 1组的特征与POD 7组进行比较。
POD 1组和POD 7组的死亡率分别为每10000例麻醉3.6例和7.8例。POD 1死亡率的发生率高于手术当周的任何其他日子。POD 1组大量输血、术中心脏骤停和术中使用肾上腺素的发生率高于POD 7组。在成人中,POD 1组急诊手术的比例高于POD 7组。POD 1组的主要死亡原因是低血容量性和心源性休克,而POD 7组是分布性休克。与人为因素相关的死亡率在POD 1组(15.3%)比POD 7组(6.1%)更常见。
POD 1死亡率的特征与POD 2 - 7死亡率不同。术后早期死亡的很大一部分归因于POD 1死亡率。与人为因素相关的原因与POD 1死亡率更相关,表明有很大的改进空间。