[肿瘤细胞增殖参数的预测意义]
[Predictive significance of parameters of tumor cell proliferation].
作者信息
Kotel'nikov V M
出版信息
Eksp Onkol. 1989;11(5):3-9.
PMID:2676470
Abstract
Recent publications on prognostic significance of tumour cell proliferation parameters (mitotic index, 3H-thymidine labelling index, cell cycle distributions using DNA-measurements) in certain human tumours are reviewed. Data on acute leukaemia are controversial. In all other haematological and non-haematological malignancies the cell proliferation parameters correlated inversely with survival rate of patients and with the duration of the relapse-free period. Practical application of these data are discussed.
摘要
本文综述了近期有关某些人类肿瘤中肿瘤细胞增殖参数（有丝分裂指数、3H-胸腺嘧啶核苷标记指数、使用DNA测量的细胞周期分布）预后意义的出版物。关于急性白血病的数据存在争议。在所有其他血液系统和非血液系统恶性肿瘤中，细胞增殖参数与患者生存率及无复发生存期呈负相关。文中还讨论了这些数据的实际应用。
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