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胃切除术后十二指肠瘘:13例新病例的回顾性研究

Duodenal fistula after gastrectomy: Retrospective study of 13 new cases.

作者信息

Cornejo María de los Ángeles, Priego Pablo, Ramos Diego, Coll Magdalena, Ballestero Araceli, Galindo Julio, García-Moreno Francisca, Rodríguez Gloria, Carda Pedro, Lobo Eduardo

机构信息

Cirugía General y Digestivo, Hospital Universitario Ramón y Cajal de Madrid, Espaa.

Cirugía General y Digestivo, Hospital Ramón y Cajal, España.

出版信息

Rev Esp Enferm Dig. 2016 Jan;108(1):20-6. doi: 10.17235/reed.2015.3928/2015.

Abstract

INTRODUCTION

Duodenal stump fistula (DSF) after gastrectomy has a low incidence but a high morbidity and mortality, and is therefore one of the most aggressive and feared complications of this procedure.

MATERIAL AND METHODS

We retrospectively evaluated all DSF occurred at our hospital after carrying out a gastrectomy for gastric cancer, between January 1997 and December 2014. We analyzed demographic, oncologic, and surgical variables, and the evolution in terms of morbidity, mortality and hospital stay.

RESULTS

In the period covered in this study, we performed 666 gastrectomies and observed DSF in 13 patients (1.95%). In 8 of the 13 patients (61.5%) surgery was the treatment of choice and in 5 cases (38.5%) conservative treatment was carried out. Postoperative mortality associated with DSF was 46.2% (6 cases). In the surgical group, 3 patients developed severe sepsis with multiple organ failure, 2 patients presented a major hematemesis which required endoscopic haemostasis, 1 patient had an evisceration and another presented a subphrenic abscess requiring percutaneous drainage. Six patients (75%) died despite surgery, with 3 deaths in the first 24 hours of postoperative care. The 2 patients who survived after the second surgical procedure had a hospital stay of 45 and 84 days respectively. In the conservative treatment group the cure rate was 100% with no significant complications and an average postoperative hospital stay of 39.5 days (range, 26-65 days).

CONCLUSION

FMD is an unusual complication but it is associated with a high morbidity and mortality. In our experience, conservative management has shown better results compared with surgical treatment.

摘要

引言

胃切除术后十二指肠残端瘘(DSF)发生率低,但发病率和死亡率高,因此是该手术最严重且令人恐惧的并发症之一。

材料与方法

我们回顾性评估了1997年1月至2014年12月在我院因胃癌行胃切除术后发生的所有DSF病例。我们分析了人口统计学、肿瘤学和手术变量,以及发病率、死亡率和住院时间方面的演变情况。

结果

在本研究涵盖的时间段内,我们共进行了666例胃切除术,其中13例患者(1.95%)发生了DSF。13例患者中有8例(61.5%)选择手术治疗,5例(38.5%)进行了保守治疗。与DSF相关的术后死亡率为46.2%(6例)。在手术组中,3例患者发生严重脓毒症伴多器官功能衰竭,2例患者出现大量呕血需要内镜止血,1例患者发生脏器脱出,另1例患者出现膈下脓肿需要经皮引流。6例患者(75%)尽管接受了手术仍死亡,其中3例在术后护理的前24小时内死亡。第二次手术后存活的2例患者住院时间分别为45天和84天。在保守治疗组中,治愈率为100%,无明显并发症,术后平均住院时间为39.5天(范围为26 - 65天)。

结论

DSF是一种不常见的并发症,但发病率和死亡率高。根据我们的经验,与手术治疗相比,保守治疗效果更好。

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