Guziński Maciej, Kurcz Jacek, Tupikowski Krzysztof, Antosz Ewelina, Słowik Paulina, Garcarek Jerzy
Department of General and Interventional Radiology and Neuroradiology, Chair of Radiology, Wroclaw Medical University, Poland.
Department of Urology and Oncological Urology, Wroclaw Medical University, Poland.
Adv Clin Exp Med. 2015 Sep-Oct;24(5):837-43. doi: 10.17219/acem/29143.
Renal arterial embolization (RAE) is one of the adjunctive methods in the treatment of renal tumors. Embolization is performed in patients prior to nephrectomy, in patients with inoperable renal tumors as palliative treatment.
The purpose of the study was to present and to analyze our own experiences in the embolization of renal tumors.
A retrospective analysis of 33 patients treated using RAE between 2011 and 2013 was carried out. In 30 cases (91%), embolization was performed due to renal carcinoma and in 3 cases (9%) due to angiomyolipoma. In 11 patients intervention was performed as a palliative procedure because of advanced disease. Histoacrylic glue, polyvinyl alcohol, sponge pledgets and embolization coils were used for embolization.
In 20 patients (61%), selective RAE was performed, whereas superselective RAE was carried out in 13 patients (39%). The technical success rate of RAE was 100%. In one case the procedure was complicated by reflux of the histoacrylic glue into the common femoral artery with its embolization that required surgical embolectomy. We used histoacrylic glue in 26 embolizations (79%), in 19 procedures (58%) as the only embolization agent. Polyvinyl alcohol was used in 10 procedures (30%), gelatin sponge pledgets and absolute ethanol in 6 patients (18%). In 4 cases (12%), coils were implemented. In 22 patients (67%), one or more components of postembolization syndrome (PES) developed. In all 22 patients with PES (100%), severe lumbar pain was observed and administration of analgesics proved necessary. In 10 patients treated by palliative embolization, both a regression of macrohaematuria and an increase in hemoglobin level were observed. In 10 further patients, the creatinine level decreased following RAE.
RAE is an effective and minimally-invasive intervention burdened with low risk of major complications. PES occurs in about two-third of patients. In the majority of patients after palliative embolization, haematuria decreases and the quality of life improves.
肾动脉栓塞术(RAE)是治疗肾肿瘤的辅助方法之一。栓塞术可在肾切除术之前对患者进行,也可用于无法手术切除的肾肿瘤患者的姑息治疗。
本研究旨在介绍并分析我们自己在肾肿瘤栓塞治疗方面的经验。
对2011年至2013年间接受RAE治疗的33例患者进行回顾性分析。其中30例(91%)因肾癌接受栓塞治疗,3例(9%)因肾血管平滑肌脂肪瘤接受栓塞治疗。11例患者因病情晚期接受姑息性介入治疗。使用组织黏合剂、聚乙烯醇、明胶海绵条和栓塞弹簧圈进行栓塞。
20例患者(61%)接受了选择性RAE,13例患者(39%)接受了超选择性RAE。RAE的技术成功率为100%。1例患者术中出现组织黏合剂反流至股总动脉并导致栓塞,需行手术取栓。我们在26次栓塞(79%)中使用了组织黏合剂,其中19次(58%)将其作为唯一的栓塞剂。10次操作(30%)使用了聚乙烯醇,6例患者(18%)使用了明胶海绵条和无水乙醇。4例(12%)使用了弹簧圈。22例患者(67%)出现了栓塞后综合征(PES)的一种或多种症状。在所有22例出现PES的患者(100%)中,均观察到严重的腰痛,因此有必要给予镇痛治疗。在10例接受姑息性栓塞治疗的患者中,肉眼血尿减轻,血红蛋白水平升高。另外10例患者在RAE后肌酐水平下降。
RAE是一种有效且微创的干预措施,主要并发症风险较低。约三分之二的患者会出现PES。在大多数接受姑息性栓塞治疗的患者中,血尿减少,生活质量提高。