Xu Rui-Hua, Shen Lin, Li Jin, Xu Jian-Ming, Bi Feng, Ba Yi, Bai Li, Shu Yong-Qian, Liu Tian-Shu, Li Yu-Hong, Bai Chun-Mei, Yuan Xiang-Lin, Zhang Jun, Chen Gong, Zhou Ai-Ping, Yuan Ying, Wang Xi-Jing, Qian Xiao-Ping, Deng Yan-Hong
Sun Yat-sen University Cancer Center; State Key Laboratory of Oncology in South China, Collaborative Innovation Center of Cancer Medicine, Guangzhou, 510060, Guangdong, P. R. China.
Department of Medical Oncology, Sun Yat-sen University Cancer Center, 651 Dongfeng Road East, Guangzhou, 510060, Guangdong, P. R. China.
Chin J Cancer. 2016 Jan 14;35:13. doi: 10.1186/s40880-015-0067-x.
The impact of maintenance therapy on progression-free survival and overall survival as well as quality of life of Chinese patients with metastatic colorectal cancer has long been under discussion. Recently, some phase III clinical trials have revealed that maintenance therapy can significantly prolong the progression-free survival while maintain an acceptable safety profile. Based on this evidence and common treatment practice in China, we now generated one Expert Consensus on Maintenance Treatment for Metastatic Colorectal Cancer in China to further specify the necessity of maintenance therapy, suitable candidates for such treatment, and appropriate regimens.
维持治疗对中国转移性结直肠癌患者无进展生存期、总生存期及生活质量的影响长期以来一直备受讨论。近期，一些Ⅲ期临床试验表明，维持治疗可显著延长无进展生存期，同时保持可接受的安全性。基于这一证据以及中国的常见治疗实践，我们制定了《中国转移性结直肠癌维持治疗专家共识》，以进一步明确维持治疗的必要性、适合接受此类治疗的患者以及合适的治疗方案。
