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食管平滑肌瘤的诊断与综合治疗:77例临床分析

Diagnosis and comprehensive treatment of esophageal leiomyoma: clinical analysis of 77 patients.

作者信息

Wang Yun-Xi, Zhang Jing, Liu Yi, Liu Yang, Chu Xiang-Yang, Lu Zhong-Sheng, Wang Zhan-Bo, Tong Xin-Yuan

机构信息

Department of Thoracic Surgery, The General Hospital of The Chinese People's Liberation Army Beijing 100853, China.

Department of Gastroenterology, The General Hospital of The Chinese People's Liberation Army Beijing 100853, China.

出版信息

Int J Clin Exp Med. 2015 Oct 15;8(10):17214-20. eCollection 2015.

Abstract

To investigate the diagnosis and comprehensive treatment of esophageal leiomyoma. The clinical data of 77 cases of esophageal leiomyoma patients were analyzed between 2005 and 2013. Its diagnosis, treatment and prognosis were analyzed. 39 cases of patients were with eating choking feeling, 18 cases presented with chest pain and weight loss and 20 cases without any symptoms. Preoperative endoscopic ultrasonography of each patient was diagnosed as possibility of esophageal submucosal tumor. 3 All patients underwent tumor enucleation, in which tumor electrotomy under gastroscope were done for 2 cases, complete video-assisted thoracoscopic (CVATS) resection of tumor for 24 cases, thoracoscope assisted small incision tumor resection for 29 cases, conventional thoracic tumor resection for 22 cases. The comparison and the difference of complete video-assisted thoracoscopic surgery group and the thoracoscope assisted small incision group for the operation time, bleeding volume, drainage volume, extubation time, hospitalization time and fasting time were not statistically significant (P < 0.05). All the patients recovered well and postoperative pathology of each patient was esophageal leiomyoma. They were followed up for 6 months to 8 years, average for 4 years, not recurrence of esophageal leiomyoma. Endoscopic ultrasonography is the most accurate method in diagnosis of esophageal leiomyoma. Esophageal leiomyoma which less than 1.0 cm in diameter, regular shape, originated in the muscularis mucosa, endoscopic electrotomy can be used as the preferred; Surgical operation is the main treatment of esophageal leiomyoma, three kinds of operation way has its own corresponding clinical indications, according to the clinical characteristics of patients and operator' habits to choose the corresponding operation way, all can achieve good treatment effect.

摘要

探讨食管平滑肌瘤的诊断与综合治疗。分析2005年至2013年77例食管平滑肌瘤患者的临床资料,对其诊断、治疗及预后进行分析。39例患者有进食哽噎感,18例有胸痛及体重减轻,20例无任何症状。术前对每位患者行内镜超声检查诊断为食管黏膜下肿瘤可能性。所有患者均行肿瘤摘除术,其中2例行胃镜下肿瘤电切术,24例行完全电视胸腔镜(CVATS)肿瘤切除术,29例行胸腔镜辅助小切口肿瘤切除术,22例行传统开胸肿瘤切除术。完全电视胸腔镜手术组与胸腔镜辅助小切口组在手术时间、出血量、引流量、拔管时间、住院时间及禁食时间方面比较,差异无统计学意义(P>0.05)。所有患者恢复良好,术后病理均为食管平滑肌瘤。随访6个月至8年,平均4年,食管平滑肌瘤无复发。内镜超声检查是诊断食管平滑肌瘤最准确的方法。直径小于1.0 cm、形态规则、起源于黏膜肌层的食管平滑肌瘤,可首选内镜电切术;手术是食管平滑肌瘤的主要治疗方法,三种手术方式各有相应临床适应证,应根据患者临床特点及术者习惯选择相应手术方式,均可取得良好治疗效果。

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