Marsh J L, Vannier M W
Division of Plastic and Reconstructive Surgery, Cleft Palate and Craniofacial Deformities Institute, St. Louis, MO 63110.
J Craniofac Genet Dev Biol. 1989;9(1):61-75.
Computer-assisted medical imaging technologies provide new tools for the study of congenital craniofacial deformities. Three-dimensional surface reconstructions have been developed to simplify the interpretation and improve the utility of CT scans of the head. While 3-D reconstructions initially were applied to assist clinical management of craniofacial deformities, these images now are finding utility in the study of unique anomalies, the definition of group characteristics for dysmorphic heads, the differentiation of similar phenotypes, and the documentation of the effects of cranial surgery on craniofacial growth. These findings should assist the formulation and evaluation of hypotheses regarding mechanisms of congenital malformation and deformation.
计算机辅助医学成像技术为先天性颅面畸形的研究提供了新工具。三维表面重建技术已得到发展,以简化头部CT扫描的解读并提高其效用。虽然三维重建最初用于辅助颅面畸形的临床管理,但这些图像现在在独特异常的研究、畸形头部群体特征的定义、相似表型的区分以及颅骨手术对颅面生长影响的记录方面都有应用。这些发现应有助于关于先天性畸形和变形机制假说的形成与评估。