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误诊为多器官脓肿的小儿间变性大细胞淋巴瘤:一例报告及文献复习

Pediatric anaplastic large cell lymphoma misdiagnosed as multiple organ abscesses: a case report and literature review.

作者信息

Yang Wenmin, Zuo Yunlong, Yang Yiyu, Tao Jianping, Hong Jie, Wu Zhiyuan, Chen Feiyan, Dang Run, Liang Yufeng, Li Yang, Liu Dabo

机构信息

Guangzhou Women and Children's Medical Center Guangzhou 510115, Guangdong, China.

The First Affiliated Hospital of Zhongshan University Guangzhou 510115, Guangdong, China.

出版信息

Int J Clin Exp Med. 2015 Oct 15;8(10):19509-16. eCollection 2015.

Abstract

We report the case of a 6-year-old male with fever, left maxillofacial swelling, cervical and mediastinal masses, and lymphadenopathy who developed respiratory failure and shock caused by tracheal compression and superior vena cava reflux disorder. The initial diagnosis was maxillary sinus, cervical, and mediastinal abscesses. Initial treatments included maxillary sinus abscess resection, neck abscess incision drainage, and antibiotics. Anaplastic large cell lymphoma (ALCL) was diagnosed ultimately according to pathological and immunohistochemical examination of cervical lesion biopsy tissue. We analyze the reasons for misdiagnosis by comparing clinical and pathological features of ALCL to other systemic illnesses that cause lymphadenopathy.

摘要

我们报告了一例6岁男性患者,其有发热、左颌面部肿胀、颈部和纵隔肿块以及淋巴结病,因气管受压和上腔静脉回流障碍而发展为呼吸衰竭和休克。最初诊断为上颌窦、颈部和纵隔脓肿。初始治疗包括上颌窦脓肿切除术、颈部脓肿切开引流术及使用抗生素。最终根据颈部病变活检组织的病理及免疫组化检查诊断为间变性大细胞淋巴瘤(ALCL)。我们通过比较ALCL与其他导致淋巴结病的全身性疾病的临床和病理特征来分析误诊原因。

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Infant anaplastic lymphoma: case report and review of the literature.
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本文引用的文献

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Anaplastic large cell lymphoma in children and adolescents.儿童和青少年间变性大细胞淋巴瘤
Pediatr Hematol Oncol. 2013 Sep;30(6):509-19. doi: 10.3109/08880018.2013.805347. Epub 2013 Jun 12.
4
Anaplastic large cell lymphoma: an unusual presentation in a 7-year-old girl.间变性大细胞淋巴瘤:一名7岁女孩的不寻常表现。
Pediatr Dermatol. 2012 Jul-Aug;29(4):498-503. doi: 10.1111/j.1525-1470.2011.01465.x. Epub 2011 Oct 4.
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Anaplastic large-cell lymphoma, T-/null-cell type.间变性大细胞淋巴瘤,T/无细胞型。
Oncologist. 2006 Jul-Aug;11(7):831-40. doi: 10.1634/theoncologist.11-7-831.

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