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胎儿有心跳且β-hCG水平极高的剖宫产瘢痕部位异位妊娠的保守治疗

Conservative Management of Cesarean Scar Ectopic Pregnancy with Fetal Heart Activity and a Very High β-hCG.

作者信息

McLaren Rodney, McCalla Sandra, Irani Mohamad

机构信息

Department of Obstetrics and Gynecology, Maimonides Medical Center, Brooklyn, NY 11219, USA.

Ronald O. Perelman and Claudia Cohen Center for Reproductive Medicine, Weill Cornell Medical Center, New York, NY 10021, USA.

出版信息

Case Rep Obstet Gynecol. 2015;2015:959876. doi: 10.1155/2015/959876. Epub 2015 Dec 6.

Abstract

Cesarean scar ectopic pregnancy (CSP) is a rare type of ectopic pregnancy that is growing in incidence. The diagnosis of most CSP occurs when patients present in unstable conditions requiring surgical management and leading sometimes to hysterectomy. It has been shown that medical management is a safe option for early diagnosed hemodynamically stable CSP. However, no cases of CSP with β-hCG higher than 62,000 IU/L, conservatively treated, have been reported. We report the case of a 29-year-old patient who presented for her first prenatal visit at 13-week gestation and was diagnosed with CSP with present fetal heart tones and a quantitative β-hCG of 144,337 IU/L. She was treated with bilateral uterine artery embolization and systemic methotrexate. Her β-hCG significantly decreased and became undetectable within 10 weeks. We propose that patients with CSP with very high β-hCG and fetal heart activity can be offered conservative or fertility preserving management.

摘要

剖宫产瘢痕部位异位妊娠(CSP)是一种罕见的异位妊娠类型,其发病率正在上升。大多数CSP在患者病情不稳定需要手术治疗,有时甚至导致子宫切除时才得以诊断。研究表明,对于早期诊断的血流动力学稳定的CSP,药物治疗是一种安全的选择。然而,尚无β-hCG高于62,000 IU/L且接受保守治疗的CSP病例报道。我们报告一例29岁患者,孕13周首次产前检查时被诊断为CSP,当时可闻及胎心音,定量β-hCG为144,337 IU/L。她接受了双侧子宫动脉栓塞和全身甲氨蝶呤治疗。她的β-hCG显著下降,在10周内降至检测不到的水平。我们建议,对于β-hCG非常高且有胎心活动的CSP患者,可以提供保守治疗或保留生育功能的治疗。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/826c/4684849/f9c76b05bf3c/CRIOG2015-959876.001.jpg

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