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[原发性睾丸横纹肌肉瘤:一例报告]

[Primary testicular rhabdomyosarcoma: A case report].

作者信息

Mejía-Salas Jesús Alberto, Sánchez-Corona Hugo, Priego-Niño Alejandro, Cárdenas-Rodríguez Edgar, Sánchez-Galindo José Antonio

机构信息

Servicio de Urología, Instituto Mexicano del Seguro Social, Unidad Médica de Alta Especialidad, Hospital de Especialidades del Centro Médico Nacional Manuel Ávila Camacho, Puebla, Puebla, México.

Servicio de Urología, Instituto Mexicano del Seguro Social, Unidad Médica de Alta Especialidad, Hospital de Especialidades del Centro Médico Nacional Manuel Ávila Camacho, Puebla, Puebla, México.

出版信息

Cir Cir. 2017 Mar-Apr;85(2):143-147. doi: 10.1016/j.circir.2015.09.007. Epub 2016 Jan 8.

Abstract

BACKGROUND

Rhabdomyosarcoma is the most common sarcoma of soft tissues in childhood and adolescence, with an annual incidence of 4-7 cases per million children aged 15. Embryonal rhabdomyosarcoma is common in adults younger than 30 years, and are usually presented as a large painless, palpable mass (> 5cm). Survival in the case of paratesticular sarcoma in men is approximately 50%.

CLINICAL CASE

Male 27 years of age with no history of importance, was seen in a clinic with an increased, painless, left testicular volume 3 years onset. Intrascrotal left testicle increased volume, with dimensions of 20×12×8cm, a stone and left inguinal node in induratum measuring 2×2cm. Microscopically, it showed a pattern of an embryonal rhabdomyosarcoma with left inguinal node metastases.

CONCLUSION

Early diagnosis of testicular tumours, and especially of primary intratesticular rhabdomyosarcomas, and aggressive surgical treatment in combination with chemotherapy reduces the incidence of local recurrence and may improve the rate of disease-free survival and overall survival in adult patients with metastases.

摘要

背景

横纹肌肉瘤是儿童和青少年时期最常见的软组织肉瘤,15岁以下儿童的年发病率为每百万4 - 7例。胚胎型横纹肌肉瘤在30岁以下成年人中较为常见,通常表现为一个大的无痛、可触及的肿块(>5cm)。男性睾丸旁肉瘤患者的生存率约为50%。

临床病例

一名27岁男性,无重要病史,因左侧睾丸无痛性增大3年就诊于诊所。左侧阴囊内睾丸体积增大,大小为20×12×8cm,有结石,左侧腹股沟淋巴结硬结,大小为2×2cm。显微镜检查显示为胚胎型横纹肌肉瘤伴左侧腹股沟淋巴结转移。

结论

早期诊断睾丸肿瘤,尤其是原发性睾丸内横纹肌肉瘤,并积极进行手术治疗联合化疗,可降低局部复发率,并可能提高成年转移患者的无病生存率和总生存率。

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