Turk J Med Sci. 2015;45(6):1374-9. doi: 10.3906/sag-1312-5.
BACKGROUND/AIM: Reduction mammoplasty is a common surgical procedure. We report the incidence of nonproliferative and proliferative breast lesions in breast reduction specimens from a single institution over a 6-year period.
The histopathology reports of all patients were analyzed. The clinical and histopathological findings of the patients were recorded.
Between 2004 and 2010, 106 patients underwent breast reduction. Fifty-six patients (52.8%) had proliferative breast lesions, 84 patients (79.2%) had nonproliferative lesions, 8 patients (7.5%) had columnar cell lesions without atypia, 61 patients (57.5%) had columnar cell lesions with atypia, 5 patients (4.7%) had atypical ductal hyperplasia, and 6 patients (5.6%) had lobular carcinoma in situ. No invasive breast cancer was identified.
In Turkey, there is limited evidence regarding the role of histopathological analysis in reduction mammoplasty. Moreover, none of the previous studies determined columnar cell lesion rates in reduction mammoplasty patients. The detection of significantly elevated columnar cell lesions, with or without atypia, especially in patients under the age of 40, increases the importance of screening tests, especially in Turkey, which has a high incidence of breast cancer in early ages, and addresses the need to starting screening tests early in these patients.
背景/目的:乳房缩小术是一种常见的外科手术。我们报告了在 6 年期间,一家机构的乳房缩小标本中非增生性和增生性乳房病变的发生率。
分析了所有患者的组织病理学报告。记录了患者的临床和组织病理学发现。
2004 年至 2010 年间,106 名患者接受了乳房缩小术。56 名患者(52.8%)存在增生性乳房病变,84 名患者(79.2%)存在非增生性病变,8 名患者(7.5%)存在无非典型柱状细胞病变,61 名患者(57.5%)存在有非典型柱状细胞病变,5 名患者(4.7%)存在非典型导管增生,6 名患者(5.6%)存在乳腺小叶原位癌。未发现浸润性乳腺癌。
在土耳其,关于组织病理学分析在乳房缩小术中的作用的证据有限。此外,以前的研究均未确定乳房缩小术患者中柱状细胞病变的发生率。尤其是在年龄小于 40 岁的患者中,检测到明显升高的柱状细胞病变,无论是否存在非典型性,都增加了筛查试验的重要性,尤其是在乳腺癌发病率较高的土耳其,这需要在这些患者中尽早开始筛查试验。