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954例缩乳标本的组织病理学结果讨论

Discussion of Histopathological Findings of 954 Breast Reduction Specimens.

作者信息

Bas Soysal, Oner Cagatay, Aydin Ali Can, Ucak Ramazan, Sirvan Selami Serhat, Karsidag Semra

机构信息

Department of Plastic, Reconstructive and Aesthetic Surgery, University of Health Sciences Turkey, Sisli Hamidiye Etfal Teaching and Research Hospital, Istanbul, Turkey.

Department of Pathology, University of Health Sciences Turkey, Sisli Hamidiye Etfal Teaching and Research Hospital, Istanbul, Turkey.

出版信息

Sisli Etfal Hastan Tip Bul. 2021 Mar 17;55(1):42-48. doi: 10.14744/SEMB.2020.33349. eCollection 2021.

Abstract

OBJECTIVES

Breast reduction is a frequently sought procedure by patients and one of the most commonly performed operations by plastic surgeons. Follow-up of histopathological results after reduction mammoplasty is very important. This study aimed to evaluate the histopathological results of patients undergoing bilateral reduction mammoplasty to determine the incidence of breast lesions and risk factors of high-risk breast lesions.

METHODS

477 patients who underwent reduction mammoplasty in the plastic surgery department between October 2013 and January 2020 were included in this study. Patients were evaluated according to age, body mass index (BMI), comorbidity factors, tobacco use, family history and histopathological findings.

RESULTS

The mean age of patients was 42.43±12.05 years. Body mass index ranged from 23 to 34.6. As for comorbidity factors, 12 patients had hypertension, five patients had asthma and six patients had diabetes mellitus. Seventeen patients (3.6%) were smokers, and 25 (5.2%) patients had a family history of breast cancer. Among the patients, 2.3% were 20 years and under, 17.1% were between 21 and 30 years old, 21.5% were between 31 and 40 years old, 33.1% were between 41 and 50 years old, 18.2% were between 51 and 60 years old, and 7.5% were 60 years and above. 85.4% of histopathological findings consisted of normal breast tissue and nonproliferative breast lesion breast lesions. The incidences of proliferative breast lesions, atypical hyperplasia and in situ lesions were calculated as 5.7%, 2% and 0.4%, respectively. The mean follow-up period was 3.8±1.6 years.

CONCLUSION

Although preoperative breast cancer screening methods are used before the reduction mammoplasty, high-risk lesions may be encountered afterwards. One of the biggest advantages of reduction mammoplasty in addition to psychophysiological recovery is breast cancer risk reduction.

摘要

目的

乳房缩小术是患者常寻求的手术,也是整形外科医生最常开展的手术之一。乳房缩小成形术后组织病理学结果的随访非常重要。本研究旨在评估接受双侧乳房缩小成形术患者的组织病理学结果,以确定乳腺病变的发生率及高危乳腺病变的危险因素。

方法

本研究纳入了2013年10月至2020年1月间在整形外科接受乳房缩小成形术的477例患者。根据年龄、体重指数(BMI)、合并症因素、吸烟情况、家族史和组织病理学结果对患者进行评估。

结果

患者的平均年龄为42.43±12.05岁。体重指数范围为23至34.6。合并症方面,12例患者患有高血压,5例患者患有哮喘,6例患者患有糖尿病。17例患者(3.6%)吸烟,25例患者(5.2%)有乳腺癌家族史。患者中,2.3%年龄在20岁及以下,17.1%年龄在21至30岁之间,21.5%年龄在31至40岁之间,33.1%年龄在41至50岁之间,18.2%年龄在51至60岁之间,7.5%年龄在60岁及以上。85.4%的组织病理学结果为正常乳腺组织和非增殖性乳腺病变。增殖性乳腺病变、非典型增生和原位病变的发生率分别为5.7%、2%和0.4%。平均随访期为3.8±1.6年。

结论

尽管在乳房缩小成形术前采用了乳腺癌术前筛查方法,但术后仍可能遇到高危病变。乳房缩小成形术除了心理生理恢复外的最大优势之一是降低乳腺癌风险。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/106b/8085449/5b546e525cb0/MBSEH-55-42-g001.jpg

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