Chalikias George, Drosos Ioannis, Tziakas Dimitrios N
University Cardiology Department, Medical School, Democritus University of Thrace, Dragana, GR-68131, Alexandroupolis, Greece.
Cardiovasc Drugs Ther. 2016 Apr;30(2):215-28. doi: 10.1007/s10557-015-6635-0.
Contrast-induced acute kidney injury (CI-AKI) is defined as an abrupt deterioration in renal function associated with the administration of iodinated contrast media. This type of acute kidney injury is frequently encountered as a complication of percutaneous coronary intervention (PCI) and is associated with adverse short- and long-term outcomes including mainly mortality, cardiovascular morbidity and prolongation of hospitalization. The incidence of CI-AKI after PCI ranges from 2 to 20 % according to baseline kidney function. It may also range according to the clinical setting, being higher after emergency PCI. The primary manifestation is a small decline in kidney function, occurring 1 to 3 days after the procedure. Kidney function usually returns to preexisting levels within 7 days. Incidence of acute renal failure requiring dialysis following PCI is rare (<1 %). The present article aims to review up-to-date published data concerning diagnosis, definition, epidemiology and prognosis of this novel in-hospital epidemic.
对比剂诱导的急性肾损伤（CI-AKI）定义为与使用碘化造影剂相关的肾功能突然恶化。这种类型的急性肾损伤常作为经皮冠状动脉介入治疗（PCI）的并发症出现，并与不良的短期和长期后果相关，主要包括死亡率、心血管疾病发病率和住院时间延长。根据基线肾功能，PCI后CI-AKI的发生率为2%至20%。其发生率也可能因临床情况而异，在急诊PCI后更高。主要表现为肾功能轻度下降，发生在术后1至3天。肾功能通常在7天内恢复到先前水平。PCI后需要透析的急性肾衰竭发生率很低（<1%）。本文旨在综述有关这一新型院内流行病的诊断、定义、流行病学和预后的最新发表数据。
