Yuge Ryo, Kitadai Yasuhiko, Tanaka Shinji, Uraoka Naohiro, Sentani Kazuhiro, Yasui Wataru, Chayama Kazuaki
Department of Gastroenterology and Metabolism, Graduate School of Biomedical and Health Sciences, Hiroshima University, Japan.
Intern Med. 2016;55(2):135-9. doi: 10.2169/internalmedicine.55.5937. Epub 2016 Jan 15.
A 63-year-old man with abdominal discomfort was referred to our hospital. Colonoscopy revealed a hemispherical-shaped protruding cecal mass of approximately 10 mm in size with a normal mucosal surface. Biopsy specimens showed nodules consisting of the proliferation of atypical lymphoid cells. Mucosa-associated lymphoid tissue (MALT) lymphoma was diagnosed based on the histological and immunohistochemical findings. Since upper gastrointestinal endoscopy demonstrated Helicobacter pylori-associated atrophic gastritis, eradication therapy was administered. The cecal mass disappeared completely within three months after triple therapy. Therefore, H. pylori eradication therapy may be a useful treatment option for cecal MALT lymphoma.
一名63岁男性因腹部不适前来我院就诊。结肠镜检查发现盲肠有一个大小约10毫米的半球形突出肿物，黏膜表面正常。活检标本显示由非典型淋巴细胞增殖形成的结节。根据组织学和免疫组化结果诊断为黏膜相关淋巴组织（MALT）淋巴瘤。由于上消化道内镜检查显示有幽门螺杆菌相关性萎缩性胃炎，遂给予根除治疗。三联疗法后三个月内，盲肠肿物完全消失。因此，幽门螺杆菌根除治疗可能是盲肠MALT淋巴瘤的一种有效治疗选择。
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