Mould D R, D'Haens G, Upton R N
Projections Research Inc., Phoenixville, Pennsylvania, USA.
Inflammatory Bowel Disease Centre Academic Medical Centre 1105 AZ, Amsterdam, The Netherlands.
Clin Pharmacol Ther. 2016 Apr;99(4):405-18. doi: 10.1002/cpt.334. Epub 2016 Feb 15.
Dashboard systems for clinical decision support integrate data from multiple sources. These systems, the newest in a long line of dose calculators and other decision support tools, utilize Bayesian approaches to fully individualize dosing using information gathered through therapeutic drug monitoring. In the treatment of inflammatory bowel disease patients with infliximab, dashboards may reduce therapeutic failures and treatment costs. The history and future development of modern Bayesian dashboard systems is described.
用于临床决策支持的仪表板系统整合了来自多个来源的数据。这些系统是一长串剂量计算器和其他决策支持工具中的最新成员,它们利用贝叶斯方法,通过治疗药物监测收集的信息来完全个性化给药。在使用英夫利昔单抗治疗炎症性肠病患者时,仪表板可能会减少治疗失败和治疗成本。本文描述了现代贝叶斯仪表板系统的历史和未来发展。