Wahn U
Ther Umsch. 1989 Sep;46(9):625-32.
Beside pharmacotherapy specific hyposensitization is well accepted in the treatment of allergic airway diseases. During the therapy allergen extracts are injected in low concentrations subcutaneously, and dosage is gradually increased in order to induce clinical tolerance in patients. For pollinosis the efficacy of the therapy is well documented, although its immunological mechanisms are not known up to now. So far, its value for the treatment of bronchial asthma is still discussed controversially. The effectiveness of oral hyposensitization has not been demonstrated yet.
除药物治疗外,特异性脱敏疗法在过敏性气道疾病的治疗中也被广泛接受。在治疗过程中,将低浓度的变应原提取物皮下注射,剂量逐渐增加,以诱导患者产生临床耐受性。对于花粉症,该疗法的疗效已有充分记录,但其免疫机制至今尚不清楚。到目前为止,其在支气管哮喘治疗中的价值仍存在争议。口服脱敏疗法的有效性尚未得到证实。