Chu J Y, Ding J F, Liu Y Z, Zhu B T, Chu Y H
Yao Xue Xue Bao. 1989;24(2):95-8.
In the hope to find new superagonists of LHRH, here we report the synthesis of six analogs by changing residue 5 of [D-Trp6 (or D-Arg6), des-Gly10]-LHRH-EA. For the convenience of comparison, the known compound [D-Trp6, desGly10]-LHRH-EA was also synthesized.
为了寻找新的促黄体生成激素释放激素(LHRH)超级激动剂,我们在此报告通过改变[D-色氨酸6(或D-精氨酸6),去甘氨酸10]-LHRH-EA的第5位残基合成六种类似物。为便于比较,还合成了已知化合物[D-色氨酸6,去甘氨酸10]-LHRH-EA。