Bautista-Molano Wilson, Landewé Robert B M, Londoño John, Romero-Sanchez Consuelo, Valle-Oñate Rafael, van der Heijde Désirée
Rheumatology Department, Leiden University Medical Center, Leiden, The Netherlands.
Rheumatology Department, School of Medicine, HMC/UMNG, Transversal 3 No. 49-00 3th floor, Bogotá, Colombia.
Clin Rheumatol. 2016 Jul;35(7):1759-67. doi: 10.1007/s10067-016-3184-2. Epub 2016 Jan 21.
The objective of this study was to investigate the performance of classification criteria sets (Assessment of SpondyloArthritis international Society (ASAS), European Spondylarthropathy Study Group (ESSG), and Amor) for spondyloarthritis (SpA) in a clinical practice cohort in Colombia and provide insight into how rheumatologists follow the diagnostic path in patients suspected of SpA. Patients with a rheumatologist's diagnosis of SpA were retrospectively classified according to three criteria sets. Classification rate was defined as the proportion of patients fulfilling a particular criterion. Characteristics of patients fulfilling and not fulfilling each criterion were compared. The ASAS criteria classified 81 % of all patients (n = 581) as having either axial SpA (44 %) or peripheral SpA (37 %), whereas a lower proportion met ESSG criteria (74 %) and Amor criteria (53 %). There was a high degree of overlap among the different criteria, and 42 % of the patients met all three criteria. Patients fulfilling all three criteria sets were older (36 vs. 30 years), had more SpA features (3 vs. 1 features), and more frequently had a current or past history of back pain (77 vs. 43 %), inflammatory back pain (47 vs. 13 %), enthesitis (67 vs. 26 %), and buttock pain (37 vs. 13 %) vs. those not fulfilling any criteria. HLA-B27, radiographs, and MRI-SI were performed in 77, 59, and 24 % of the patients, respectively. The ASAS criteria classified more patients as having SpA in this Colombian cohort when the rheumatologist's diagnosis is used as an external standard. Although physicians do not perform HLA-B27 or imaging in all patients, they do require these tests if the clinical symptoms fall short of confirming SpA and suspicion remains.
本研究的目的是调查分类标准集(国际脊柱关节炎评估协会(ASAS)、欧洲脊柱关节病研究组(ESSG)和阿莫尔标准)在哥伦比亚临床实践队列中对脊柱关节炎(SpA)的评估表现,并深入了解风湿病学家对疑似SpA患者的诊断路径。对经风湿病学家诊断为SpA的患者,根据三种标准集进行回顾性分类。分类率定义为符合特定标准的患者比例。比较了符合和不符合各标准的患者特征。ASAS标准将所有患者(n = 581)中的81%分类为患有轴向SpA(44%)或外周SpA(37%),而符合ESSG标准的比例较低(74%),符合阿莫尔标准的比例为(53%)。不同标准之间存在高度重叠,42%的患者符合所有三种标准。与不符合任何标准的患者相比,符合所有三种标准集的患者年龄更大(36岁对30岁),具有更多的SpA特征(3个特征对1个特征),并且更频繁地有当前或过去的背痛病史(77%对43%)、炎性背痛(47%对13%)、附着点炎(67%对26%)和臀部疼痛(37%对13%)。分别有77%、59%和24%的患者进行了HLA - B₂₇检测、X线检查和MRI - SI检查。当以风湿病学家的诊断作为外部标准时,ASAS标准在这个哥伦比亚队列中分类出更多患有SpA的患者。尽管医生并非对所有患者都进行HLA - B₂₇检测或影像学检查,但如果临床症状不足以确诊SpA且仍有怀疑,他们确实需要这些检查。