Jafarian Ali, Elyasinia Fezzeh, Keramati Mohammad Reza, Ahmadi Farham, Parsaei Reza
Associate Professor of Surgery, Department of Surgery, Tehran University of Medical Sciences, Tehran, Iran.
MD, Assistant Professor of Surgery, Department of Surgery, Tehran University of Medical Sciences, Tehran, Iran.
Med J Islam Repub Iran. 2015 Oct 12;29:278. eCollection 2015.
Peripheral arterial disease is a source of morbidity and mortality. Surgical vascular reconstruction is a treatment option but probability of failure and complications are important concerns. In this study, we evaluated outcome of surgical infrainguinal reconstruction and factors affecting graft patency for a period of one year.
In this cohort study, 85 consecutive patients with chronic ischemia who underwent lower extremity surgical vascular reconstruction (including 52 femoropopliteal and 25 femorofemoral bypass) from March 2007 to Feb 2009 were recruited. Graft patency was evaluated before discharge from hospital and one year after the surgical operation using duplex ultrasonography. Association between possible risk factors and graft patency were evaluated.
In general, 71% (37 patients) of femoropopliteal and 52% (13 patients) of femorofemoral reconstructions were patent during the follow up period. Diabetes mellitus, hypertension, smoking, opium use and ischemic heart disease were significantly associated with decreased rate of patency (p<0.05).
Assessing risk factors that predict perioperative mortality and graft patency is essential for selecting patients that would benefit from surgery. Omitting surgical reconstruction and endovascular intervention may be preferable especially when multiple risk factors are present or in the absence of critical limb ischemia.
外周动脉疾病是发病和死亡的一个原因。外科血管重建是一种治疗选择,但失败的可能性和并发症是重要的关注点。在本研究中,我们评估了外科股动脉以下重建的结果以及影响移植物通畅一年的因素。
在这项队列研究中,招募了2007年3月至2009年2月期间连续85例接受下肢外科血管重建(包括52例股腘动脉旁路移植术和25例股股动脉旁路移植术)的慢性缺血患者。在出院前和手术后一年使用双功超声评估移植物通畅情况。评估了可能的危险因素与移植物通畅之间的关联。
总体而言,在随访期间,股腘动脉重建的71%(37例患者)和股股动脉重建的52%(13例患者)移植物保持通畅。糖尿病、高血压、吸烟、使用鸦片和缺血性心脏病与通畅率降低显著相关(p<0.05)。
评估预测围手术期死亡率和移植物通畅的危险因素对于选择将从手术中获益的患者至关重要。尤其是当存在多种危险因素或不存在严重肢体缺血时,省略外科重建和血管内介入可能更可取。